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SRD5A2 gene

Known as: Steroid-5-Alpha-Reductase, Alpha Polypeptide 2 (3-oxo-5 Alpha-Steroid Delta 4-Dehydrogenase Alpha 2) Gene, 3-oxo-5-alpha-steroid 4-dehydrogenase 2, SRD5A2 
This gene is involved in androgen metabolism and sexual differentiation.
National Institutes of Health

Related topics

Related topics

4 relations
Androgen Metabolism ProcessHypospadiasOxidation-ReductionTestosterone 5-alpha-Reductase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Altered methylation pattern of the SRD5A2 gene in cerebrospinal fluid of post- Finasteride patients: a pilot study
1Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Milan, Italy; 2Unit of Endocrinology… 
2018
2018
65例染色体核型为46, XY的尿道下裂患者 AR 和 SRD5A2 基因突变分析
目的观察临床诊断为尿道下裂、染色体核型为46，XY的患者AR及SRD5A2基因突变情况，探讨尿道下裂患者的遗传病因。 方法运用Sanger测序技术对2015-2017年在四川省人民医院就诊的65例临床诊断为尿道下裂、染色体核型为46，XY的患者AR… 
2018
2018
Mutational Analysis of SRD5A2 and AR Genes in Indian Children with 46 XY Disorders of Sex Development
2017
2017
A Novel p.Arg179Ser (c.537 G>T) Heterozygotes Mutation on Exon 3 Of SRD5A2 Gene Accompany With Biotidinase Deficiency In Case With Ambiguous External Genitalia
The SRD5A2 gene that encodes SRD5A2 enzyme is placed on chromosome 2p23. The coding region of the gene includes 5 exons that are… 
2014
2014
AB215. Variants in the SRD5A2 gene are associated with quality of semen
Spermatogenesis and sperm maturation are androgen-dependent processes. Steroid 5α-reductase (SRD5A) is a key enzyme converting… 
2012
2012
Association of V89L SRD5A2 polymorphism with craving and serum leptin levels in male alcohol addicts
A causal role of sex hormones in the onset and course of alcohol dependence is well established. We recently demonstrated that… 
2006
2006
Regulation of 5alpha-reductase type II (SRD5A2) gene expression by phytoestrogens
142 DHT is the main growth promoting factor in the prostate and is an androgenic stimulus in males. A long period of exposure to… 
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