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Testosterone 5-alpha-Reductase

Known as: 5 alpha Reductase, Testosterone, delta4 3 ketosteroid 5alpha Oxidoreductase, 5Alpha Reductase, Steroid 
3-oxo-5-alpha-steroid 4-dehydrogenase 2 (254 aa, ~28 kDa) is encoded by the human SRD5A2 gene. This protein plays a role in sexual differentiation… Expand
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Steroidal estrogens, originating principally from human excretion, are likely to play a major role in causing widespread… Expand
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Highly Cited
2000
Highly Cited
2000
Familial idiopathic nephrotic syndromes represent a heterogeneous group of kidney disorders, and include autosomal recessive… Expand
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Review
1994
Review
1994
BIOCHEMICAL PROPERTIES OF STEROID Sa-REDUCTASE . . . . . . . . . . . . 30 Protein Structure… Expand
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Highly Cited
1994
Highly Cited
1994
The outcome of the first steroid treatment course was prospectively studied in a regional cohort of 196 patients with Crohn's… Expand
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Highly Cited
1993
Highly Cited
1993
The synthesis of dihydrotestosterone is catalyzed by steroid 5 alpha-reductase isozymes, designated types 1 and 2. Mutation of… Expand
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Review
1993
Review
1993
In the 20 yr since it was established that impairment of dihydrotestosterone formation is the cause of a rare form of human… Expand
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Highly Cited
1992
Highly Cited
1992
Two isozymes of steroid 5 alpha-reductase encoded by separate loci catalyze the conversion of testosterone to dihydrotestosterone… Expand
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Review
1992
Review
1992
The human prostate tumor cell line LNCaP contains an abnormal androgen receptor system with broad steroid binding specificity… Expand
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Highly Cited
1990
Highly Cited
1990
LNCaP prostate tumor cells contain an abnormal androgen receptor system. Progestagens, estradiol and anti-androgens can compete… Expand
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Highly Cited
1985
Highly Cited
1985
Nonclassical steroid 21-hydroxylase deficiency is an autosomal recessive disorder that is defined by clinical and hormonal… Expand
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