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Bile Acid Biosynthesis Pathway
Known as:
Primary bile acid biosynthesis
, bile acid formation
, bile acid anabolism
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The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile. [GOC…
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National Institutes of Health
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Related topics
Related topics
13 relations
ACOX2 wt Allele
AMACR protein, human
CYP39A1 protein, human
CYP39A1 wt Allele
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Fibroblast Growth Factor 19 and 7α-Hydroxy-4-Cholesten-3-one in the Diagnosis of Patients With Possible Bile Acid Diarrhea
S. Pattni
,
Gordon W Brydon
,
T. Dew
,
J. Walters
Clinical and Translational Gastroenterology
2012
Corpus ID: 14291615
OBJECTIVES:Increased colonic bile acids can cause chronic diarrhea. Bile acid diarrhea (BAD) is treatable by sequestrants, and…
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Highly Cited
2006
Highly Cited
2006
Hypocholesterolemic action of pre-germinated brown rice in hepatoma-bearing rats.
Daiki Miura
,
Yukihiko Ito
,
Aya Mizukuchi
,
M. Kise
,
H. Aoto
,
K. Yagasaki
Life Science
2006
Corpus ID: 36399659
Highly Cited
1995
Highly Cited
1995
Increase of deoxycholate in supersaturated bile of patients with cholesterol gallstone disease and its correlation with de novo syntheses of cholesterol and bile acids in liver, gallbladder emptying…
J. Shoda
,
B. He
,
+5 authors
J. Sjövall
Hepatology
1995
Corpus ID: 37989568
A total of 100 nonobese and normolipidemic subjects (29 control subjects, 49 patients with cholesterol stones [CSs], and 22…
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Highly Cited
1991
Highly Cited
1991
Molecular structure of rat hepatic 3 alpha-hydroxysteroid dehydrogenase. A member of the oxidoreductase gene family.
A. Stolz
,
Mitra Rahimi-Kianin
,
Detlev Ameisq
,
Elaine Chanll
,
M. Ronk
,
J. Shively
Journal of Biological Chemistry
1991
Corpus ID: 25104526
Highly Cited
1990
Highly Cited
1990
Regulation of bile acid synthesis. IV. Interrelationship between cholesterol and bile acid biosynthesis pathways.
W. Pandak
,
D. Heuman
,
P. Hylemon
,
Z. Vlahcevic
Journal of Lipid Research
1990
Corpus ID: 31297397
Under most experimental conditions, the activities of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA reductase) and cholesterol 7…
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Highly Cited
1988
Highly Cited
1988
Regulation of bile acid synthesis. I. Effects of conjugated ursodeoxycholate and cholate on bile acid synthesis in chronic bile fistula rat
D. Heuman
,
Carmen R. Hernandez
,
P. Hylemon
,
W. Kubaska
,
Constance Hartman
,
Z. Vlahcevic
Hepatology
1988
Corpus ID: 2388437
Bile acid synthesis is thought to be regulated by a negative feedback mechanism which is presumably dependent upon the flux of…
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Highly Cited
1986
Highly Cited
1986
Ketoconazole blocks bile acid synthesis in hepatocyte monolayer cultures and in vivo in rat by inhibiting cholesterol 7 alpha-hydroxylase.
H. Princen
,
C. Huijsmans
,
F. Kuipers
,
R. Vonk
,
H. Kempen
Journal of Clinical Investigation
1986
Corpus ID: 23815976
In cultured hepatocytes conversion of [4-14C]cholesterol into bile acids was dose dependently reduced by the antimycotic drug…
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Highly Cited
1976
Highly Cited
1976
Effects of ethinyl estradiol and phenobarbital on bile acid synthesis and biliary bile acid and cholesterol excretion.
R. Davis
,
F. Kern
Gastroenterology
1976
Corpus ID: 39615850
Highly Cited
1975
Highly Cited
1975
Sterol balance studies in the rat. Effects of dietary cholesterol and beta-sitosterol on sterol balance and rate-limiting enzymes of sterol metabolism.
R. Raicht
,
R. Raicht
,
+5 authors
E. Mosbach
Biochimica et Biophysica Acta
1975
Corpus ID: 7873273
Highly Cited
1973
Highly Cited
1973
Induced alterations in the rate-limiting enzymes of hepatic cholesterol and bile acid synthesis in the hamster.
L. Schoenfield
,
G. Bonorris
,
P. Ganz
Journal of Laboratory and Clinical Medicine
1973
Corpus ID: 33693272
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