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Bile Acid Biosynthesis Pathway

Known as: Primary bile acid biosynthesis, bile acid formation, bile acid anabolism 
The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile. [GOC… 
National Institutes of Health

Related topics

Related topics

13 relations
ACOX2 wt AlleleAMACR protein, humanCYP39A1 protein, humanCYP39A1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Diversity in gut bacterial community of school-age children in Asia
Asia differs substantially among and within its regions populated by diverse ethnic groups, which maintain their own respective… 
Highly Cited
2011
Highly Cited
2011
FGF19 Regulates Cell Proliferation, Glucose and Bile Acid Metabolism via FGFR4-Dependent and Independent Pathways
Fibroblast growth factor 19 (FGF19) is a hormone-like protein that regulates carbohydrate, lipid and bile acid metabolism. At… 
Highly Cited
2011
Highly Cited
2011
Dual farnesoid X receptor/TGR5 agonist INT‐767 reduces liver injury in the Mdr2−/− (Abcb4−/−) mouse cholangiopathy model by promoting biliary HCO  3− output
Chronic cholangiopathies have limited therapeutic options and represent an important indication for liver transplantation. The… 
Highly Cited
2004
Highly Cited
2004
Ligand-activated Pregnane X Receptor Interferes with HNF-4 Signaling by Targeting a Common Coactivator PGC-1α
Previous studies show that feedback inhibition of bile acid production by bile acids is mediated by multiple mechanisms… 
Highly Cited
2003
Highly Cited
2003
Hepatoprotection by the farnesoid X receptor agonist GW4064 in rat models of intra- and extrahepatic cholestasis.
Farnesoid X receptor (FXR) is a bile acid-activated transcription factor that is a member of the nuclear hormone receptor… 
Highly Cited
2002
Highly Cited
2002
Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis.
Highly Cited
2001
Highly Cited
2001
Down-regulation of Cholesterol 7α-Hydroxylase (CYP7A1) Gene Expression by Bile Acids in Primary Rat Hepatocytes Is Mediated by the c-Jun N-terminal Kinase Pathway*
Cholesterol 7α-hydroxylase (CYP7A1), the rate-limiting enzyme in the neutral pathway of bile acid biosynthesis, is feedback… 
Review
2000
Review
2000
Role of osmoregulation in the actions of taurine
Summary. Taurine regulates an unusual number of biological phenomena, including heart rhythm, contractile function, blood… 
Review
2000
Review
2000
Consumption of fermented and nonfermented dairy products: effects on cholesterol concentrations and metabolism.
The objective of this article was to review existing literature concerning the effects and mechanisms of action of fermented… 
Highly Cited
1970
Highly Cited
1970
Biochemical site of regulation of bile acid biosynthesis in the rat.
The production of bile salts by rat liver is regulated by a feedback mechanism, but it is not known which enzyme controls… 
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