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Bile Acid Biosynthesis Pathway

Known as: Primary bile acid biosynthesis, bile acid formation, bile acid anabolism 
The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile. [GOC… 
National Institutes of Health

Related topics

Related topics

13 relations
ACOX2 wt AlleleAMACR protein, humanCYP39A1 protein, humanCYP39A1 wt Allele

Papers overview

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Highly Cited
2012
Highly Cited
2012
Fibroblast Growth Factor 19 and 7α-Hydroxy-4-Cholesten-3-one in the Diagnosis of Patients With Possible Bile Acid Diarrhea
OBJECTIVES:Increased colonic bile acids can cause chronic diarrhea. Bile acid diarrhea (BAD) is treatable by sequestrants, and… 
Highly Cited
2006
Highly Cited
2006
Hypocholesterolemic action of pre-germinated brown rice in hepatoma-bearing rats.
Highly Cited
1995
Highly Cited
1995
Increase of deoxycholate in supersaturated bile of patients with cholesterol gallstone disease and its correlation with de novo syntheses of cholesterol and bile acids in liver, gallbladder emptying…
A total of 100 nonobese and normolipidemic subjects (29 control subjects, 49 patients with cholesterol stones [CSs], and 22… 
Highly Cited
1991
Highly Cited
1991
Molecular structure of rat hepatic 3 alpha-hydroxysteroid dehydrogenase. A member of the oxidoreductase gene family.
Highly Cited
1990
Highly Cited
1990
Regulation of bile acid synthesis. IV. Interrelationship between cholesterol and bile acid biosynthesis pathways.
Under most experimental conditions, the activities of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA reductase) and cholesterol 7… 
Highly Cited
1988
Highly Cited
1988
Regulation of bile acid synthesis. I. Effects of conjugated ursodeoxycholate and cholate on bile acid synthesis in chronic bile fistula rat
Bile acid synthesis is thought to be regulated by a negative feedback mechanism which is presumably dependent upon the flux of… 
Highly Cited
1986
Highly Cited
1986
Ketoconazole blocks bile acid synthesis in hepatocyte monolayer cultures and in vivo in rat by inhibiting cholesterol 7 alpha-hydroxylase.
In cultured hepatocytes conversion of [4-14C]cholesterol into bile acids was dose dependently reduced by the antimycotic drug… 
Highly Cited
1976
Highly Cited
1976
Effects of ethinyl estradiol and phenobarbital on bile acid synthesis and biliary bile acid and cholesterol excretion.
Highly Cited
1975
Highly Cited
1975
Sterol balance studies in the rat. Effects of dietary cholesterol and beta-sitosterol on sterol balance and rate-limiting enzymes of sterol metabolism.
Highly Cited
1973
Highly Cited
1973
Induced alterations in the rate-limiting enzymes of hepatic cholesterol and bile acid synthesis in the hamster.
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