• Publications
  • Influence
Mechanisms in endocrinology: Genetics of FSH action: a 2014-and-beyond view.
OBJECTIVE To assess the pharmacogenetic potential of FSH for infertility treatment. DESIGN Review of the literature and genomic databases. METHODS Single-nucleotide polymorphism (SNP) assessed:Expand
  • 67
  • 6
Stress and immune response in the mussel Mytilus galloprovincialis.
The present study investigates the effects on immune-related parameters of various stress factors (air exposure, mechanical stress, high temperature and extreme salinity conditions) faced by theExpand
  • 78
  • 3
Effects of the marine toxins okadaic acid and palytoxin on mussel phagocytosis.
The present study analyzes the effects of the marine toxins okadaic acid (OA) and palytoxin (PTX) on the phagocytic activity of immunocytes from the mussel Mytilus galloprovincialis. In particular,Expand
  • 36
  • 3
Algal toxin yessotoxin signalling pathways involve immunocyte mussel calcium channels
A fragment of a putative L‐type Ca2+ channel has been identified by molecular biology experiments in immunocytes from the mussel Mytilus galloprovincialis. Using the cell permeable and Ca2+‐specificExpand
  • 22
  • 3
Clinical Applications of Gonadotropins in the Female: Assisted Reproduction and Beyond.
Gonadotropins (LH, FSH, and hCG) act in concert in the regulation of female reproductive system. Exploiting this influence, they are part of the assisted reproductive technique protocols. In thisExpand
  • 15
  • 2
The polycystic ovary syndrome evolutionary paradox: a genome-wide association studies-based, in silico, evolutionary explanation.
CONTEXT Polycystic ovary syndrome (PCOS) is a common female endocrine disorder characterized by phenotypes ranging from hyperandrogenism to metabolic disorders, more prevalent in people ofExpand
  • 36
  • 2
Effects of polymorphisms in gonadotropin and gonadotropin receptor genes on reproductive function
Gonadotropins, the action of which is mediated at the level of their gonadal receptors, play a key role in sexual development, reproductive functions and in metabolism. The involvement of theExpand
  • 36
  • 2
Human Luteinizing Hormone and Chorionic Gonadotropin Display Biased Agonism at the LH and LH/CG Receptors
Human luteinizing hormone (LH) and chorionic gonadotropin (hCG) have been considered biologically equivalent because of their structural similarities and their binding to the same receptor; theExpand
  • 36
  • 1
Genetics of gonadotropins and their receptors as markers of ovarian reserve and response in controlled ovarian stimulation.
Several controlled ovarian stimulation (COS) protocols have been developed to increase the yield of mature oocytes retrieved in assisted reproductive techniques (ARTs). The ovarian reserve (OR)Expand
  • 12
  • 1
Pharmacogenetics of G-protein-coupled receptors variants: FSH receptor and infertility treatment.
Infertility treatment may represent a paradigmatic example of precision medicine. Follicle-stimulating hormone (FSH) has been proposed as a valuable therapeutic option both in males and in females,Expand
  • 10
  • 1