SORL1 protein, human

Known as: sortilin-related receptor, L(DLR class) A repeats-containing, human, LR11, SorLA-1 protein, human 
Sortilin-related receptor (2214 aa, ~248 kDa) is encoded by the human SORL1 gene. This protein is involved in both endocytosis and protein… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2016
0246819962016

Papers overview

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Highly Cited
2007
Highly Cited
2007
SorLA/LR11 (250 kDa) is the largest and most composite member of the Vps10p-domain receptors, a family of type 1 proteins… (More)
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2007
2007
Apolipoprotein A-V is a potent modulator of plasma triacylglycerol levels. To investigate the molecular basis for this phenomenon… (More)
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2007
2007
OBJECTIVE LR11 (aka sorLA) is a multifunctional neuronal receptor that binds apolipoprotein E and interacts with amyloid… (More)
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Highly Cited
2006
Highly Cited
2006
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline and neuropathological… (More)
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2006
2006
SorLA/LR11 is a sorting receptor that regulates the intracellular transport and processing of the amyloid precursor protein (APP… (More)
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Highly Cited
2006
Highly Cited
2006
LR11 is an ApoE receptor that is enriched in the brain. We have shown that LR11 is markedly downregulated in patients with… (More)
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2006
2006
BACKGROUND The mammalian Vps10p sorting receptor family is a group of 5 type I membrane homologs (Sortilin, SorLA, and SorCS1-3… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Genetic, epidemiologic, and biochemical evidence suggests that apolipoprotein E, low-density lipoprotein receptors… (More)
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2001
2001
Since the molecular identification of the low density lipoprotein receptor (LDLR), an ever increasing number of related proteins… (More)
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1999
1999
A novel receptor, SorCS, was isolated from murine brain. It shows homology to the mosaic receptor SorLA and the neurotensin… (More)
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