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SORL1 protein, human

Known as: sortilin-related receptor, L(DLR class) A repeats-containing, human, LR11, SorLA-1 protein, human 
Sortilin-related receptor (2214 aa, ~248 kDa) is encoded by the human SORL1 gene. This protein is involved in both endocytosis and protein… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
sorLA is a sorting receptor for amyloid precursor protein (APP) genetically linked to Alzheimer's disease (AD). Retromer, an… Expand
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Review
2009
Review
2009
  • Guido Hermey
  • Cellular and Molecular Life Sciences
  • 2009
  • Corpus ID: 11835340
The family of mammalian type-I transmembrane receptors containing a Vps10p domain contains five members, Sortilin, SorCS1, SorCS2… Expand
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Review
2008
Review
2008
VPS10P-domain receptors, such as SORLA and sortilin, constitute a recently identified class of type-1 receptors that are… Expand
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Highly Cited
2007
Highly Cited
2007
The recycling of the amyloid precursor protein (APP) from the cell surface via the endocytic pathways plays a key role in the… Expand
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Highly Cited
2007
Highly Cited
2007
ABSTRACT SorLA/LR11 (250 kDa) is the largest and most composite member of the Vps10p-domain receptors, a family of type 1… Expand
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Highly Cited
2006
Highly Cited
2006
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline and neuropathological… Expand
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Highly Cited
2006
Highly Cited
2006
LR11 is an ApoE receptor that is enriched in the brain. We have shown that LR11 is markedly downregulated in patients with… Expand
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Highly Cited
2005
Highly Cited
2005
sorLA (Sorting protein-related receptor) is a type-1 membrane protein of unknown function that is expressed in neurons. Its… Expand
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Highly Cited
2001
Highly Cited
2001
We previously isolated and sequenced the ∼250-kDa type 1 receptor sorLA/LR11, a mosaic protein with elements characterizing the… Expand
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Highly Cited
1996
Highly Cited
1996
The 39-40-kDa receptor-associated protein (RAP) binds to the members of the low density lipoprotein receptor gene family and… Expand
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