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An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest
In this study, we have assessed the validity and reliability of an automated labeling system for subdividing the human cerebral cortex on magnetic resonance images into gyral based regions of interest (ROIs). Expand
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The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease
The National Institute on Aging and the Alzheimer's Association charged a workgroup with the task of revising the 1984 criteria for Alzheimer's disease (AD) dementia. The workgroup sought to ensureExpand
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Effects of Age, Sex, and Ethnicity on the Association Between Apolipoprotein E Genotype and Alzheimer Disease: A Meta-analysis
Objective. —To examine more closely the association between apolipoprotein E (APOE) genotype and Alzheimer disease (AD) by age and sex in populations of various ethnic and racial denominations. DataExpand
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Neuropathological alterations in Alzheimer disease.
The neuropathological hallmarks of Alzheimer disease (AD) include "positive" lesions such as amyloid plaques and cerebral amyloid angiopathy, neurofibrillary tangles, and glial responses, andExpand
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National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease
A consensus panel from the United States and Europe was convened recently to update and revise the 1997 consensus guidelines for the neuropathologic evaluation of Alzheimer's disease (AD) and otherExpand
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Profound Loss of Layer II Entorhinal Cortex Neurons Occurs in Very Mild Alzheimer’s Disease
The entorhinal cortex (EC) plays a crucial role as a gateway connecting the neocortex and the hippocampal formation. Layer II of the EC gives rise to the perforant pathway, the major source of theExpand
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Live tissue intrinsic emission microscopy using multiphoton-excited native fluorescence and second harmonic generation
Multicolor nonlinear microscopy of living tissue using two- and three-photon-excited intrinsic fluorescence combined with second harmonic generation by supermolecular structures produces images withExpand
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Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice
We investigated synaptic communication and plasticity in hippocampal slices from mice overexpressing mutated 695-amino-acid human amyloid precursor protein (APP695SWE), which show behavioral andExpand
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Primary age-related tauopathy (PART): a common pathology associated with human aging
We recommend a new term, “primary age-related tauopathy” (PART), to describe a pathology that is commonly observed in the brains of aged individuals. Many autopsy studies have reported brains withExpand
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