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SMS gene

Known as: SMS, SpS, MRSR 
National Institutes of Health

Related topics

Related topics

2 relations
MENTAL RETARDATION, X-LINKED, SNYDER-ROBINSON TYPESpermine Synthase

Papers overview

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Highly Cited
2020
Highly Cited
2020
Spermine synthase and MYC cooperate to maintain colorectal cancer cell survival by repressing Bim expression
Dysregulation of polyamine metabolism has been linked to the development of colorectal cancer (CRC), but the underlying mechanism… 
Review
2014
Review
2014
The function of spermine
Polyamines play important roles in cell physiology including effects on the structure of cellular macromolecules, gene expression… 
Highly Cited
2011
Highly Cited
2011
Polyamine metabolic canalization in response to drought stress in Arabidopsis and the resurrection plant Craterostigma plantagineum
In this work, we have studied the transcriptional profiles of polyamine biosynthetic genes and analyzed polyamine metabolic… 
Highly Cited
2008
Highly Cited
2008
Crystal Structure of Human Spermine Synthase
The crystal structures of two ternary complexes of human spermine synthase (EC 2.5.1.22), one with 5′-methylthioadenosine and… 
Review
2006
Review
2006
Aminopropyltransferases: function, structure and genetics.
Aminopropyltransferases use decarboxylated S-adenosylmethionine as an aminopropyl donor and an amine acceptor to form polyamines… 
Highly Cited
2004
Highly Cited
2004
Spermine Synthesis Is Required for Normal Viability, Growth, and Fertility in the Mouse*
Spermidine is essential for viability in eukaryotes but the importance of the longer polyamine spermine has not been established… 
Highly Cited
2002
Highly Cited
2002
Characterization of the spermidine synthase‐related gene family in Arabidopsis thaliana
Highly Cited
2001
Highly Cited
2001
Effect of polyamine depletion on caspase activation: a study with spermine synthase-deficient cells.
Activation of the caspase proteases represents a central point in apoptosis. The requirement for spermine for the processes… 
Highly Cited
1998
Highly Cited
1998
Spermine is not essential for growth of Saccharomyces cerevisiae: identification of the SPE4 gene (spermine synthase) and characterization of a spe4 deletion mutant.
Highly Cited
1980
Highly Cited
1980
Studies of inhibition of rat spermidine synthase and spermine synthase.
1. S-Adenosyl-l-methionine, S-adenosyl-l-homocysteine, 5'-methylthioadenosine and a number of analogues having changes in the… 
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