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Spermine Synthase
Known as:
Synthetase, Spermine
, Spermine Synthetase
, Synthase, Spermine
Â
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An enzyme that catalyzes the transfer of the propylamine moiety from 5'-deoxy-5'-S-(3-methylthiopropylamine)sulfonium adenosine to spermidine in the…Â
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Topic mentions per year
Topic mentions per year
1953-2016
0
1
2
1953
2015
Related topics
Related topics
10 relations
In Blood
Process of secretion
SMS gene
administration & dosage
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Related mentions per year
Related mentions per year
1936-2018
1940
1960
1980
2000
2020
Spermine Synthase
physiological aspects
chemical synthesis
standards characteristics
SMS gene
Process of secretion
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Potential application of SERS for arsenic speciation in biological matrices.
MingWei Yang
,
Shannon M. Matulis
,
Lawrence H. Boise
,
Anthony J. McGoron
,
Yong Cai
Analytical and bioanalytical chemistry
2017
Speciation of arsenic is usually carried out using chromatography-based methods coupled with spectroscopic determination; however…Â
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2016
2016
Revealing the Effects of Missense Mutations Causing Snyder-Robinson Syndrome on the Stability and Dimerization of Spermine Synthase
Yunhui Peng
,
J. H. Norris
,
C J Schwartz
,
Emil Alexov
,
W. Cho
International journal of molecular sciences
2016
Missense mutations in spermine synthase (SpmSyn) protein have been shown to cause the Snyder-Robinson syndrome (SRS). Depending…Â
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2014
2014
Rational Design of Small-Molecule Stabilizers of Spermine Synthase Dimer by Virtual Screening and Free Energy-Based Approach
Zhe Zhang
,
Virginie Y. Martiny
,
+4 authors
Bridget K Wagner
PloS one
2014
Snyder-Robinson Syndrome (SRS) is a rare mental retardation disorder which is caused by the malfunctioning of an enzyme, the…Â
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2013
2013
Enhancing Human Spermine Synthase Activity by Engineered Mutations
Zhe Zhang
,
Yueli Zheng
,
Margo Petukh
,
Anthony Pegg
,
Yoshihiko Ikeguchi
,
Emil Alexov
PLoS Computational Biology
2013
Spermine synthase (SMS) is an enzyme which function is to convert spermidine into spermine. It was shown that gene defects…Â
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2012
2012
γ-glutamyl Spermine Synthetase PauA2 as a potential target of antibiotic development against Pseudomonas aeruginosa.
Xiangyu Yao
,
Congran Li
,
Jianmei Zhang
,
Chung-Dar Lu
Antimicrobial agents and chemotherapy
2012
Polyamines are absolute requirements for cell growth. When in excess, Pseudomonas aeruginosa possesses six γ-glutamylpolyamine…Â
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2011
2011
In Silico and In Vitro Investigations of the Mutability of Disease-Causing Missense Mutation Sites in Spermine Synthase
Zhe Zhang
,
J. H. Norris
,
C J Schwartz
,
Emil Alexov
PloS one
2011
BACKGROUND Spermine synthase (SMS) is a key enzyme controlling the concentration of spermidine and spermine in the cell. The…Â
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2006
2006
Consequences of Spermine Synthase or Spermidine/Spermine N- Acetyltransferase Deficiency in Polyamine Metabolism
Kirsi Niiranen
2006
A vast number of studies have linked polyamines to numerous cellular functions but less is known about the possible physiological…Â
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2005
2005
N4,N9-Dioleoyl Spermine Is a Novel Nonviral Lipopolyamine Vector for Plasmid DNA Formulation
Osama A A Ahmed
,
Noppadon Adjimatera
,
Charareh Pourzand
,
Ian S. Blagbrough
Pharmaceutical Research
2005
To study the effect of synthesized N4,N9-dioleoyl spermine on DNA condensation and then measure its transfection efficiency in…Â
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2002
2002
Interaction between nitric oxide and subsets of human T lymphocytes with differences in glutathione metabolism.
Ramon Roozendaal
,
Henk F. Kauffman
,
+4 authors
Edo Vellenga
Immunology
2002
Nitric oxide (NO) modulates human T-lymphocyte responses through several mechanisms. In the current study we show that…Â
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2001
2001
Role of ecNOS-derived NO in mediating TNF-induced endothelial barrier dysfunction.
Kevin E. Bove
,
P. Neumann
,
Nancy Gertzberg
,
A. Johnson
American journal of physiology. Lung cellular and…
2001
We tested the hypothesis that endothelial cell nitric oxide synthase (ecNOS) mediates the tumor necrosis factor (TNF)-alpha…Â
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