Expression of SSAT, a novel biomarker of tubular cell damage, increases in kidney ischemia-reperfusion injury.

@article{Zahedi2003ExpressionOS,
  title={Expression of SSAT, a novel biomarker of tubular cell damage, increases in kidney ischemia-reperfusion injury.},
  author={Kamyar Zahedi and Zhaohui Wang and Sharon Barone and Anne E. Prada and Caitlin N Kelly and Robert Anthony Casero and Naoko Yokota and Carl W. Porter and Hamid Rabb and Manoocher Soleimani},
  journal={American journal of physiology. Renal physiology},
  year={2003},
  volume={284 5},
  pages={F1046-55}
}
Ischemia-reperfusion injury (IRI) is the major cause of acute renal failure in native and allograft kidneys. Identifying the molecules and pathways involved in the pathophysiology of renal IRI will yield valuable new diagnostic and therapeutic information. To identify differentially regulated genes in renal IRI, RNA from rat kidneys subjected to an established renal IRI protocol (bilateral occlusion of renal pedicles for 30 min followed by reperfusion) and time-matched kidneys from sham… CONTINUE READING