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SLC5A1 wt Allele

Known as: NAGT, SGLT1, Solute Carrier Family 5 (Sodium/Glucose Cotransporter), Member 1 wt Allele 
Human SLC5A1 wild-type allele is located in the vicinity of either 22q13.1 or 22q12.3 and is approximately 67 kb in length. This allele, which… 
National Institutes of Health

Related topics

Related topics

6 relations
Carbohydrate MetabolismHomo sapiensLigand BindingMolecular Transport

Broader (1)

SLC5A1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Upregulation of Na+-coupled Glucose transporter SGLT1 by Tau Tubulin Kinase 2
The Tau-tubulin-kinase 2 (TTBK2) is a serine/threonine kinase expressed in various tissues including tumors. Up-regulation of… 
2007
2007
Tripeptides of RS1 (RSC1A1) Inhibit a Monosaccharide-dependent Exocytotic Pathway of Na+-d-Glucose Cotransporter SGLT1 with High Affinity*
The human gene RSC1A1 codes for a 67-kDa protein named RS1 that mediates transcriptional and post-transcriptional regulation of… 
Highly Cited
2006
Highly Cited
2006
Ligands on the string: single-molecule AFM studies on the interaction of antibodies and substrates with the Na+-glucose co-transporter SGLT1 in living cells
Atomic force microscopy (AFM) was used to probe topology, conformational changes and initial substratecarrier interactions of Na… 
Highly Cited
2006
Highly Cited
2006
Water transport by Na+‐coupled cotransporters of glucose (SGLT1) and of iodide (NIS). The dependence of substrate size studied at high resolution
The relation between substrate and water transport was studied in Na+‐coupled cotransporters of glucose (SGLT1) and of iodide… 
2001
2001
The Plasma Membrane-associated Protein RS1 Decreases Transcription of the Transporter SGLT1 in Confluent LLC-PK1 Cells*
Previously we cloned RS1, a 67-kDa polypeptide that is associated with the intracellular side of the plasma membrane. Upon co… 
1998
1998
Functional studies of the rabbit intestinal Na+/glucose carrier (SGLT1) expressed in COS-7 cells: evaluation of the mutant A166C indicates this region is important for Na+-activation of the carrier.
We have exploited two mutants of the rabbit intestinal Na+/glucose carrier SGLT1 to explore the structure/function relationship… 
1997
1997
Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation.
Tight junctions serve as the rate-limiting barrier to passive movement of hydrophilic solutes across intestinal epithelia. After… 
1995
1995
Arginine‐427 in the Na+/glucose cotransporter (SGLT1) is involved in trafficking to the plasma membrane
1995
1995
The effects of streptozotocin diabetes on sodium-glucose transporter (SGLT1) expression and function in rat jejunal and ileal villus-attached enterocytes
Rats treated with streptozotocin for 17 days were used to determine the cellular origin of enhanced brush border glucose… 
Highly Cited
1994
Highly Cited
1994
Sodium/D-glucose cotransporter charge movements involve polar residues.
Na(+)-dependent glucose transporters (SGLT1) exhibit transient carrier currents with a time constant (tau) of 2-20 ms, and the… 
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