SLC5A1 wt Allele

Known as: NAGT, SGLT1, Solute Carrier Family 5 (Sodium/Glucose Cotransporter), Member 1 wt Allele 
Human SLC5A1 wild-type allele is located in the vicinity of either 22q13.1 or 22q12.3 and is approximately 67 kb in length. This allele, which… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2017
0204019892017

Papers overview

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Highly Cited
2012
Highly Cited
2012
To clarify the physiological role of Na(+)-D-glucose cotransporter SGLT1 in small intestine and kidney, Sglt1(-/-) mice were… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Canagliflozin is a sodium glucose co-transporter (SGLT) 2 inhibitor in clinical development for the treatment of type… (More)
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Highly Cited
2000
Highly Cited
2000
We have investigated the mechanism responsible for the diffusive component of intestinal glucose absorption, the major route by… (More)
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Highly Cited
2000
Highly Cited
2000
Intestinal glucose uptake is mainly performed by the sodium-dependent glucose transporter, SGLT1. The transport activity of SGLT1… (More)
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Highly Cited
2000
Highly Cited
2000
Although it has been suggested that the intestinal glucose transporter may actively absorb dietary flavonoid glucosides, there is… (More)
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Highly Cited
1997
Highly Cited
1997
Tight junctions serve as the rate-limiting barrier to passive movement of hydrophilic solutes across intestinal epithelia. After… (More)
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Highly Cited
1995
Highly Cited
1995
The distribution of beta 1,2 N-acetylglucosaminyltransferase I (NAGT I), alpha 1,3-1,6 mannosidase II (Mann II), beta 1,4… (More)
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Highly Cited
1994
Highly Cited
1994
The major reabsorptive mechanism for D-glucose in the kidney is known to involve a low affinity high capacity Na+/glucose… (More)
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Highly Cited
1994
Highly Cited
1994
The medial Golgi enzymes, N-acetylglucosaminyltransferase I (NAGT I) and mannosidase II (Mann II), and the trans Golgi enzyme… (More)
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Highly Cited
1994
Highly Cited
1994
We report the primary structure, functional characterization, and tissue distribution of the high affinity Na+/glucose… (More)
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