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Detection and localization of individual antibody-antigen recognition events by atomic force microscopy.
A methodology has been developed for the study of molecular recognition at the level of single events and for the localization of sites on biosurfaces, in combining force microscopy with molecularExpand
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Detection and localization of single molecular recognition events using atomic force microscopy
Because of its piconewton force sensitivity and nanometer positional accuracy, the atomic force microscope (AFM) has emerged as a powerful tool for exploring the forces and the dynamics of theExpand
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Cadherin interaction probed by atomic force microscopy.
Single molecule atomic force microscopy was used to characterize structure, binding strength (unbinding force), and binding kinetics of a classical cadherin, vascular endothelial (VE)-cadherin,Expand
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Single-molecule recognition imaging microscopy.
Atomic force microscopy is a powerful and widely used imaging technique that can visualize single molecules and follow processes at the single-molecule level both in air and in solution. For maximumExpand
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Higher dispersion efficacy of functionalized carbon nanotubes in chemical and biological environments.
Aqueous dispersions of functionalized carbon nanotubes (CNTs) are now widely used for biomedical applications. Their stability in different in vitro or in vivo environments, however, depends on aExpand
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Comparison of different aminofunctionalization strategies for attachment of single antibodies to AFM cantilevers.
Atomic force microscopy (AFM) has developed into a key technique for elucidation of biological systems on the single molecular level. In particular, molecular recognition force microscopy has provenExpand
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Detection of HSP60 on the membrane surface of stressed human endothelial cells by atomic force and confocal microscopy
The highly conserved and ubiquitous heat shock proteins (HSP) are essential for the cellular homeostasis and efficiently trigger cellular responses to stress conditions. Both microbial and human HSPExpand
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Proliferation of aligned mammalian cells on laser-nanostructured polystyrene.
Biomaterial surface chemistry and nanoscale topography are important for many potential applications in medicine and biotechnology as they strongly influence cell function, adhesion andExpand
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Age determination of blood spots in forensic medicine by force spectroscopy.
We present a new tool for the estimation of the age of bloodstains, which could probably be used during forensic casework. For this, we used atomic force microscopy (AFM) for high-resolution imagingExpand
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A new, simple method for linking of antibodies to atomic force microscopy tips.
Functionalization of atomic force microscope (AFM) tips with bioligands converts them into monomolecular biosensors which can detect complementary receptor molecules on the sample surface. FlexibleExpand
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