Skip to search formSkip to main contentSkip to account menu

SLC1A2 wt Allele

Known as: Excitotoxic Amino Acid Transporter 2 Gene, GLT-1, Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 wt Allele 
Human SLC1A2 wild-type allele is located within 11p13-p12 and is approximately 169 kb in length. This allele, which encodes excitatory amino acid… 
National Institutes of Health

Related topics

Related topics

8 relations
11p13-p12Amyotrophic Lateral SclerosisHomo sapiensLigand Binding

Broader (1)

SLC1A2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
The Rates of Postmortem Proteolysis of Glutamate Transporters Differ Dramatically between Cells and between Transporter Subtypes
Glutamate transporters (GLT-1, GLAST, EAAC1) limit the actions of excitatory amino acids. Because a disturbed transporter… 
2005
2005
High-yield expression, reconstitution and structure of the recombinant, fully functional glutamate transporter GLT-1 from Rattus norvegicus.
2003
2003
WAY‐855 (3‐amino‐tricyclo[2.2.1.02.6]heptane‐1,3‐dicarboxylic acid): a novel, EAAT2‐preferring, nonsubstrate inhibitor of high‐affinity glutamate uptake
The pharmacological profile of a novel glutamate transport inhibitor, WAY‐855 (3‐amino‐tricyclo[2.2.1.02.6]heptane‐1,3… 
2002
2002
Alternative splicing of the 5′‐sequences of the mouse EAAT2 glutamate transporter and expression in a transgenic model for amyotrophic lateral sclerosis
Glutamate‐mediated neurotoxicity and a reduced expression of the excitatory amino acid transporter 2 (EAAT2) have been described… 
Highly Cited
2002
Highly Cited
2002
CNS region‐specific regulation of glial glutamate transporter expression
The neuronal cell death associated with certain neurodegenerative disorders as well as acute brain injuries is in part due to the… 
Highly Cited
2002
Highly Cited
2002
Distribution of two splice variants of the glutamate transporter GLT‐1 in rat brain and pituitary
We have performed immunocytochemistry on rat brains using a highly specific antiserum directed against the originally described… 
Highly Cited
2002
Highly Cited
2002
The Amino Terminus of the Glial Glutamate Transporter GLT-1 Interacts with the LIM Protein Ajuba
We have identified a cytoplasmic LIM protein, Ajuba, which interacts with the amino terminus of GLT-1, the most abundant plasma… 
Highly Cited
2000
Highly Cited
2000
Modulation of glutamate transporters (GLAST, GLT-1 and EAAC1) in the rat cerebellum following portocaval anastomosis
1997
1997
Functional Expression of a GLT‐1 Type Na+‐Dependent Glutamate Transporter in Rat Pinealocytes
Abstract: Pinealocytes, the neuroendocrine cells that produce melatonin, accumulate glutamate in microvesicles through a specific… 
1994
1994
Histidine 326 is critical for the function of GLT-1, a (Na+ + K+)-coupled glutamate transporter from rat brain.
Removal of glutamate from the synaptic cleft is carried out by transporter molecules located in presynaptic nerve terminals and… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)