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SLC1A2 wt Allele

Known as: Excitotoxic Amino Acid Transporter 2 Gene, GLT-1, Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 wt Allele 
Human SLC1A2 wild-type allele is located within 11p13-p12 and is approximately 169 kb in length. This allele, which encodes excitatory amino acid… 
National Institutes of Health

Related topics

Related topics

8 relations
11p13-p12Amyotrophic Lateral SclerosisHomo sapiensLigand Binding

Broader (1)

SLC1A2 gene

Papers overview

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Highly Cited
2009
Highly Cited
2009
Regulation of the Glutamate Transporter EAAT2 by PIKfyve
The Na+,glutamate cotransporter EAAT2 is expressed in astrocytes and clears glutamate from the synaptic cleft. EAAT2 dependent… 
Highly Cited
2008
Highly Cited
2008
A β-Lactam Antibiotic Dampens Excitotoxic Inflammatory CNS Damage in a Mouse Model of Multiple Sclerosis
In multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE), impairment of glial “Excitatory… 
Highly Cited
2005
Highly Cited
2005
Spinal glial glutamate transporters downregulate in rats with taxol-induced hyperalgesia
Highly Cited
2005
Highly Cited
2005
Glutamate transporter function of rat hippocampal astrocytes is impaired following the global ischemia
Review
2003
Review
2003
Theanine and glutamate transporter inhibitors enhance the antitumor efficacy of chemotherapeutic agents.
Highly Cited
2003
Highly Cited
2003
Glutamate Modifies Ion Conduction and Voltage-dependent Gating of Excitatory Amino Acid Transporter-associated Anion Channels*
Excitatory amino acid transporters (EAATs) mediate two distinct transport processes, a stoichiometrically coupled transport of… 
Highly Cited
2002
Highly Cited
2002
CNS region‐specific regulation of glial glutamate transporter expression
The neuronal cell death associated with certain neurodegenerative disorders as well as acute brain injuries is in part due to the… 
Highly Cited
2002
Highly Cited
2002
The Amino Terminus of the Glial Glutamate Transporter GLT-1 Interacts with the LIM Protein Ajuba
We have identified a cytoplasmic LIM protein, Ajuba, which interacts with the amino terminus of GLT-1, the most abundant plasma… 
Highly Cited
2000
Highly Cited
2000
The Accessibility of a Novel Reentrant Loop of the Glutamate Transporter GLT-1 Is Restricted by Its Substrate*
The excitatory neurotransmitter glutamate is removed from the synaptic cleft by several related sodium- and potassium-coupled… 
Highly Cited
2000
Highly Cited
2000
Decreased cortical levels of astrocytic glutamate transport protein GLT-1 in a rat model of posttraumatic epilepsy
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