SLC1A2 wt Allele

Known as: Excitotoxic Amino Acid Transporter 2 Gene, GLT-1, Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 wt Allele 
Human SLC1A2 wild-type allele is located within 11p13-p12 and is approximately 169 kb in length. This allele, which encodes excitatory amino acid… (More)
National Institutes of Health

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Highly Cited
2005
Highly Cited
2005
Glutamate is the principal excitatory neurotransmitter in the nervous system. Inactivation of synaptic glutamate is handled by… (More)
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Highly Cited
2002
Highly Cited
2002
Transgenic overexpression of Cu(+2)/Zn(+2) superoxide dismutase 1 (SOD1) harboring an amyotrophic lateral sclerosis (ALS)-linked… (More)
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Highly Cited
1998
Highly Cited
1998
The role of transporters in shaping the glutamate concentration in the extracellular space after synaptic release is… (More)
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Review
1998
Review
1998
Molecular biology entered the field of mammalian amino acid transporters in 1990-1991 with the cloning of the first GABA and… (More)
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Highly Cited
1996
Highly Cited
1996
Three glutamate transporters have been identified in rat, including astroglial transporters GLAST and GLT-1 and a neuronal… (More)
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Highly Cited
1995
Highly Cited
1995
The pathogenesis of sporadic amyotrophic lateral sclerosis (ALS) is unknown, but defects in synaptosomal high-affinity glutamate… (More)
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Highly Cited
1995
Highly Cited
1995
The glutamate transporters GLT-1 and GLAST were studied by immunogold labeling on ultrathin sections of rat brain tissue embedded… (More)
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Highly Cited
1994
Highly Cited
1994
The cellular and subcellular distributions of the glutamate transporter subtypes EAAC1, GLT-1, and GLAST in the rat CNS were… (More)
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Highly Cited
1994
Highly Cited
1994
Reuptake plays an important role in regulating synaptic and extracellular concentrations of glutamate. Three glutamate… (More)
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