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SLC19A1 protein, human

Known as: RFC1 (reduced folate carrier) protein, human, SLC19A1, folate transporter 1, human 
Folate transporter 1 (591 aa, ~65 kDa) is encoded by the human SLC19A1 gene. This protein plays a role in the transmembrane transport of folate.
National Institutes of Health

Related topics

Related topics

13 relations
Cellular MembraneLigand BindingLiver parenchymaMolecular Transport

Broader (1)

reduced folate carrier

Papers overview

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2020
2020
Role of Slc19a1 and Tfr2 in liver transport of iron and folate: A rat model of folate/iron deficiency followed by supplementation.
2019
2019
Analysis of the novel excretory cell expressed ECP-1 protein and its proposed ECP-1/IFC-2 fusion protein EXC-2 in the nematode Caenorhabditis elegans.
Review
2016
Review
2016
Treatable Inborn Errors of Metabolism Due to Membrane Vitamin Transporters Deficiency.
2016
2016
Treatable Inborn Errors of Metabolism Due to Membrane Vitamin Transporters Deficiency
2010
2010
PETROGRAPHIC CHARACTERIZATION OF TWO GOLD-RICH BANDED IRON FORMATIONS (BIFS) IN THE FOXE FOLT BELT
Precambrian banded iron formations (BIFs) are an important host for gold mineralization in many cratons of the world, where they… 
2007
2007
Down‐regulation of reduced folate carrier may result in folate malabsorption across intestinal brush border membrane during experimental alcoholism
Folate plays a critical role in maintaining normal metabolic, energy, differentiation and growth status of all mammalian cells… 
2006
2006
Alternative transcripts of rat slc19a1: Defective sorting and inefficient expression of alternative splicing products—an addendum
Recently, we have reported about the existence and cloning of alternative transcripts of the solute carrier 19a1 in rat liver and… 
2002
2002
Analysis of membrane topology of the human reduced folate carrier protein by hemagglutinin epitope insertion and scanning glycosylation insertion mutagenesis.
2000
2000
Characterization of a human alternatively spliced truncated reduced folate carrier increasing folate accumulation in parental leukemia cells.
Human CEM-7A cells established by gradual deprivation of leucovorin from the growth medium, display 100-fold overexpression of… 
1999
1999
Folate-restricted Conditions against Mono-and MultilayeredColon Cancer Cell Lines under Synthase Inhibitors Tomudex ( ZD 1694 ) and GW 1843 U 89 Determinants of Activity of the Antifolate Thymidylate…
The cytotoxicity and metabolic effects of two thymidylate synthase (TS) inhibitors, Tomudex (Raltitrexed, ZD1694) and GW1843U89… 
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