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SH3 and Multiple Ankyrin Repeat Domains Protein 3

Known as: ProSAP2, Proline-Rich Synapse-Associated Protein 2, Shank3 
SH3 and Multiple Ankyrin Repeat Domains Protein 3 (1741 aa, 186 kDa) is a cell communication protein that is encoded by the human SHANK3 gene and… 
National Institutes of Health

Related topics

Related topics

8 relations
Ankyrin RepeatCoiled-Coil DomainProline-Rich DomainSH3 Domain

Papers overview

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Review
2018
Review
2018
SHANK 3 haploinsufficiency : a ” common ” but underdiagnosed highly penetrant monogenic cause of autism spectrum disorders
Autism spectrum disorders (ASD) are etiologically heterogeneous, with hundreds of rare, highly penetrant mutations and genomic… 
2017
2017
VTA DA neuron excitatory synapses in Shank3 Δex4–9 mouse line
Several mutations within SHANK3 gene have been identified in Autism Spectrum Disorder patients and several studies have now… 
2017
2017
Structure of an unconventional SH3 domain from the postsynaptic density protein Shank3 at ultrahigh resolution.
2017
2017
SHANK3 Regulates Intestinal Barrier Function Through Modulating ZO-1 Expression Through the PKCε-dependent Pathway.
BACKGROUND The integrity of the gut barrier in patients with inflammatory bowel disease is known to be impaired but the exact… 
2016
2016
Zinc Stabilizes Shank3 at the Postsynaptic Density of Hippocampal Synapses
Shank3 is a postsynaptic density (PSD) scaffold protein of the Shank family. Here we use pre-embedding immunogold electron… 
2015
2015
Shank3 as a potential biomarker of antidepressant response to ketamine and its neural correlates in bipolar depression.
2014
2014
The Kvβ2 subunit of voltage-gated potassium channels is interacting with ProSAP2/Shank3 in the PSD
2011
2011
A translocation between Xq21.33 and 22q13.33 causes an intragenic SHANK3 deletion in a woman with Phelan–McDermid syndrome and hypergonadotropic hypogonadism
Chromosome 22q13 monosomy has been described as a contiguous gene syndrome. Localized in the critical region, SHANK3 is likely to… 
2009
2009
The cytoskeletal scaffold Shank3 is recruited to pathogen-induced actin rearrangements.
2004
2004
Identification of novel phosphorylation sites on postsynaptic density proteins.
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