SH3 and Multiple Ankyrin Repeat Domains Protein 3

Known as: ProSAP2, Proline-Rich Synapse-Associated Protein 2, Shank3 
SH3 and Multiple Ankyrin Repeat Domains Protein 3 (1741 aa, 186 kDa) is a cell communication protein that is encoded by the human SHANK3 gene and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2018
010203019992018

Papers overview

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Highly Cited
2013
Highly Cited
2013
Mutations in SHANK3 and large duplications of the region spanning SHANK3 both cause a spectrum of neuropsychiatric disorders… (More)
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Highly Cited
2012
Highly Cited
2012
Genetic mutations of SHANK3 have been reported in patients with intellectual disability, autism spectrum disorder (ASD) and… (More)
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Highly Cited
2011
Highly Cited
2011
Autism spectrum disorders (ASDs) comprise a range of disorders that share a core of neurobehavioural deficits characterized by… (More)
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Highly Cited
2008
Highly Cited
2008
Experience-dependent changes in the structure of dendritic spines may contribute to learning and memory. Encoded by three genes… (More)
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Highly Cited
2006
Highly Cited
2006
The postsynaptic density (PSD) is a complex assembly of proteins associated with the postsynaptic membrane that organizes… (More)
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2004
2004
Shank proteins are a family of multidomain scaffolding proteins best known for their role in organizing the postsynaptic density… (More)
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2002
2002
The ProSAP/Shank family of multidomain proteins of the postsynaptic density (PSD) can either directly or indirectly interact with… (More)
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Highly Cited
2001
Highly Cited
2001
The terminal 22q13.3 deletion syndrome is characterized by severe expressive-language delay, mild mental retardation, hypotonia… (More)
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Highly Cited
1999
Highly Cited
1999
The postsynaptic density (PSD) is crucially involved in the structural and functional organization of the postsynaptic… (More)
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Highly Cited
1999
Highly Cited
1999
We have recently isolated a novel proline-rich synapse-associated protein-1 (ProSAP1) that is highly enriched in postsynaptic… (More)
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