SH3 Domain

Known as: SH3 Domains, SRC Homology Region 3 Domain 
A region of protein sequence similarity among members of the SRC family of cytoplasmic tyrosine kinases, and other proteins. The SH3 domain is a… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2016
0102019922016

Papers overview

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Highly Cited
2004
Highly Cited
2004
The Arp2/3 complex can be independently activated to initiate actin polymerization by the VCA domain of WASP family members and… (More)
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Highly Cited
2003
Highly Cited
2003
SAP (or SH2D1A), an adaptor-like molecule expressed in immune cells, is composed almost exclusively of a Src homology 2 (SH2… (More)
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2003
2003
SH3 domains are protein recognition modules within many adaptors and enzymes. With more than 500 SH3 domains in the human genome… (More)
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Highly Cited
1999
Highly Cited
1999
Using the yeast two-hybrid system and an in vitro binding assay, we have identified a novel protein termed vinexin as a vinculin… (More)
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Highly Cited
1999
Highly Cited
1999
In yeast two-hybrid screens for proteins that bind to SNAP-25 and may be involved in exocytosis, we isolated a protein called… (More)
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Highly Cited
1998
Highly Cited
1998
Cortactin is an actin-binding protein that contains several potential signaling motifs including a Src homology 3 (SH3) domain at… (More)
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Highly Cited
1997
Highly Cited
1997
Amphiphysin is an SH3 domain-containing neuronal protein that is highly concentrated in nerve terminals where it interacts via… (More)
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Highly Cited
1996
Highly Cited
1996
Based on the prevalence of modular protein domains, such as Src homology domain 3 and 2 (SH3 and SH2), among important signaling… (More)
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Highly Cited
1994
Highly Cited
1994
Paxillin is a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix… (More)
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Highly Cited
1992
Highly Cited
1992
THE induction of the hermaphrodite vulva1 and the migration of the sex myoblasts2,3 in the nematode Caenorhabdltis elegans are… (More)
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