Yanrong Ren

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Protein-DNA recognition plays a central role in the regulation of gene expression. With the rapidly increasing number of protein-DNA complex structures available at atomic resolution in recent years, a systematic, complete, and intuitive framework to clarify the intrinsic relationship between the global binding modes of these complexes is needed. In this(More)
Quantitative structure-activity relationship (QSAR), a regression modeling methodology that establishes statistical correlation between structure feature and apparent behavior for a series of congeneric molecules quantitatively, has been widely used to evaluate the activity, toxicity and property of various small-molecule compounds such as drugs, toxicants(More)
We establish two models with Cellular Automaton (CA) to simulate the conditions of multi-lane freeways under the Keep-Right-Except-to-Pass (KRETP) rule and other improved road rules. We establish the Keep-Right-Except-to- Pass (KRETP) model, which takes into consideration human behaviors when simulating the KRETP rule in both light and heavy traffic. In(More)
In order to evaluate the nutrition value of the yak meat and to compare fatty acid of kidney fat from yak and yellow cattle, the fatty acid composition of the kidney fat from yak and yellow cattle both grown in Gansu province, China was investigated by use of gas chromatographic method. Compared with yellow cattle, the monounsaturated fatty acid and(More)
Src homology 3 (SH3) domain is a versatile protein structure module that participates in mediating various protein–protein binding events by specifically recognizing proline-rich region of diverse plasmatic proteins. Reliable and fast inference of SH3-binding partners over the human proteome are fundamentally important for our understanding of the molecular(More)
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