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Coiled-Coil Domain

Known as: Coiled-Coil, 4-3 Hydrophobic Repeat, Left-Handed Twist 
A domain that stabilizes alpha helices in proteins through a very efficient burial of hydrophobic side chains so that polar water molecules do not… 
National Institutes of Health

Related topics

Related topics

44 relations
AKAP9 protein, humanANGPT1 protein, humanAmyloid Beta Precursor Protein-Binding Protein 2Androgen-Induced Prostate Proliferative Shutoff Associated Protein

Papers overview

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Highly Cited
2001
Highly Cited
2001
FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomes.
Hrs, an essential tyrosine kinase substrate, has been implicated in intracellular trafficking and signal transduction pathways… 
Highly Cited
1999
Highly Cited
1999
Hybrid hydrogels assembled from synthetic polymers and coiled-coil protein domains
Stimuli-sensitive polymer hydrogels, which swell or shrink in response to changes in the environmental conditions, have been… 
Highly Cited
1994
Highly Cited
1994
Human mannose-binding protein carbohydrate recognition domain trimerizes through a triple α-helical coiled-coil
Human mannose-binding protein is a hexamer of trimers with each subunit consisting of an amino-terminal region rich in cysteine… 
Highly Cited
1993
Highly Cited
1993
A spring-loaded mechanism for the conformational change of influenza hemagglutinin
Highly Cited
1992
Highly Cited
1992
A coiled‐coil related protein specific for synapsed regions of meiotic prophase chromosomes.
Synaptonemal complexes (SCs) are structures that are formed between homologous chromosomes during meiotic prophase. They are… 
Highly Cited
1992
Highly Cited
1992
The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted α Helices: Crystal structure of the protein-DNA complex
Highly Cited
1990
Highly Cited
1990
Coiled-coil fibrous domains mediate ligand binding by macrophage scavenger receptor type II
THE macrophage scavenger receptor, which has been implicated in the pathogenesis of atherosclerosis1,2, has an unusually broad… 
Highly Cited
1989
Highly Cited
1989
Evidence that the leucine zipper is a coiled coil.
Recently, a hypothetical structure called a leucine zipper was proposed that defines a new class of DNA binding proteins. The… 
Highly Cited
1975
Highly Cited
1975
Tropomyosin coiled-coil interactions: evidence for an unstaggered structure.
Highly Cited
1953
Highly Cited
1953
The packing of α‐helices: simple coiled‐coils
It is shown in this paper by Crick that when -helices of the same sense pack together they will probably do so about 20° away… 
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