ANGPT1 protein, human

Known as: Angiopoietin 1, angiopoietin 1, human, ANG-1 
Angiopoietin-1 (498 aa, ~58 kDa) is encoded by the human ANGPT1 gene. This protein is involved in both signal transduction and angiogenesis.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2018
020406019962018

Papers overview

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Review
2018
Review
2018
The endothelial barrier consists of intercellular contacts localized in the cleft between endothelial cells, which is covered by… (More)
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Highly Cited
2002
Highly Cited
2002
VEGF and Angiopoietin-1 requisitely collaborate during blood vessel development. While Angiopoietin-1 obligately activates its… (More)
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Highly Cited
2000
Highly Cited
2000
Pathological increases in vascular leakage lead to edema and swelling, causing serious problems in brain tumors, in diabetic… (More)
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Highly Cited
2000
Highly Cited
2000
Inflammation is a basic pathological mechanism that underlies many diseases. An important component of the inflammatory response… (More)
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Highly Cited
2000
Highly Cited
2000
  • I Kim, H G Kim, J N So, J H Kim, H J Kwak, Gou Young Koh
  • Circulation research
  • 2000
Angiopoietin-1 (Ang1) is a strong apoptosis survival factor for endothelial cells. In this study, the receptor/second messenger… (More)
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Highly Cited
1998
Highly Cited
1998
Angiopoietin-1 (Ang1) has been recently identified as the major physiological ligand for the tyrosine kinase receptor Tie2 and… (More)
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Highly Cited
1998
Highly Cited
1998
The angiopoietins and members of the vascular endothelial growth factor (VEGF) family are the only growth factors thought to be… (More)
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Highly Cited
1998
Highly Cited
1998
Sprouting of new capillaries from pre-existing blood vessels is a hallmark of angiogenesis during embryonic development and solid… (More)
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Highly Cited
1996
Highly Cited
1996
Vascular endothelial growth factor (VEGF), which acts via members of a family of endothelial-specific receptor tyrosine kinases… (More)
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Highly Cited
1996
Highly Cited
1996
TIE2 is a receptor-like tyrosine kinase expressed almost exclusively in endothelial cells and early hemopoietic cells and… (More)
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