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SC 53116
Known as:
SC-53116
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Benzamides
Pyrroles
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Pyrrolizidine esters and amides as 5-HT4 receptor agonists and antagonists.
D. Becker
,
D. Flynn
,
+6 authors
Dai-Chang Yang
Journal of Medicinal Chemistry
2006
Corpus ID: 993414
A series of pyrrolizidine esters, amides, and ureas was prepared and tested for 5-HT(4) and 5-HT(3) receptor binding, 5-HT(4…
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2004
2004
Self-condensation of N-tert-butanesulfinyl aldimines: application to the rapid asymmetric synthesis of biologically important amine-containing compounds.
L. Schenkel
,
J. Ellman
Organic Letters
2004
Corpus ID: 22775343
[reaction: see text] Highly diastereoselective intra- and intermolecular self-condensation reactions of N-tert-butanesulfinyl…
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2004
2004
Bridgehead-methyl analog of SC-53116 as a 5-HT4 agonist.
D. Becker
,
D. Flynn
,
C. I. Villamil
Bioorganic & Medicinal Chemistry Letters
2004
Corpus ID: 38217533
1999
1999
5-HT4 receptors in isolated human corpus cavernosum?
E. Hayes
,
P. Adaikan
,
S. Ratnam
,
Sc Ng
International journal of impotence research
1999
Corpus ID: 29910525
The novel serotonin subtype-4 (5-HT4) receptor agonist, SC53116 (SC), produced a limited relaxation of noradrenaline (NA) pre…
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1997
1997
Effects of gastroprokinetic agents on gastroparesis in streptozotocin-induced diabetic rats
M. Yamano
,
T. Kamato
,
Y. Nagakura
,
K. Miyata
Naunyn-Schmiedeberg's Archives of Pharmacology
1997
Corpus ID: 9380204
Abstract The influence of diabetic hyperglycemia on solid gastric emptying in rats was examined. Diabetes was produced by…
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1997
1997
5-CT or DOI augments TRH analog-induced gastric acid secretion at the dorsal vagal complex.
S. Varanasi
,
J. Chi
,
R. Stephens
American Journal of Physiology. Regulatory…
1997
Corpus ID: 4376478
Serotonin (5-HT) interacts with thyrotropin-releasing hormone (TRH) at the dorsal vagal complex (DVC) to augment TRH-induced…
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1995
1995
Investigation of the 5-hydroxytryptamine receptor mediating the “transient” short-circuit current response in guinea-pig ileal mucosa
E. Leung
,
D. Blissard
,
M. Jett
,
R. Eglen
Naunyn-Schmiedeberg's Archives of Pharmacology
1995
Corpus ID: 13075358
Abstract5-Hydroxytryptamine (5-HT) stimulated an increase in short-circuit current (Isc) in guinea-pig isolated ileal mucosa over…
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Highly Cited
1993
Highly Cited
1993
RS 23597‐190: a potent and selective 5‐HT4 receptor antagonist
R. Eglen
,
K. Bley
,
+5 authors
E. Wong
British Journal of Pharmacology
1993
Corpus ID: 27976422
1 The pharmacological properties of RS 23597‐190 (3‐(piperdine‐1‐yl)‐propyl‐4‐amino‐5‐chloro‐2‐methoxy benzoate hydrochloride…
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1993
1993
SC-53606, a potent and selective antagonist of 5-hydroxytryptamine4 receptors in isolated rat esophageal tunica muscularis mucosae.
D. Yang
,
B. Goldstin
,
A. Moormann
,
D. Flynn
,
G. Gullikson
Journal of Pharmacology and Experimental…
1993
Corpus ID: 8761214
(1-S,8-S)-N-[(hexahydro-1H-pyrrolizin-1-yl)methyl]-6-chloroimi+ ++- dazo[1,2-a]pyridine-8-carboxamide hydrochloride (SC-53606…
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Highly Cited
1992
Highly Cited
1992
SC-53116: the first selective agonist at the newly identified serotonin 5-HT4 receptor subtype.
D. Flynn
,
D. L. Zabrowski
,
+5 authors
D. Yang
Journal of Medicinal Chemistry
1992
Corpus ID: 38072613
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