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SB 277011
Known as:
SB 277011-A
, SB-277011
, SB-277011-A
Â
Â
Topic mentions per year
Topic mentions per year
2000-2018
0
2
4
2000
2018
Related topics
Related topics
2 relations
Broader (2)
Nitriles
Tetrahydroisoquinolines
Related mentions per year
Related mentions per year
1944-2018
1940
1960
1980
2000
2020
SB 277011
Nitriles
Tetrahydroisoquinolines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Delay of ejaculation induced by SB-277011, a selective dopamine D3 receptor antagonist, in the rat.
Pierre Clément
,
Chiara Pozzato
,
Christian A. Heidbreder
,
Laurent Alexandre
,
F. Giuliano
,
Sergio Melotto
The journal of sexual medicine
2009
INTRODUCTION Dopamine (DA) plays a key role in different aspects of the male sexual response, including sexual motivation and…Â
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2007
2007
Effect of the selective dopamine D3 receptor antagonist SB-277011-A on regional c-Fos-like expression in rat forebrain.
Eric Southam
,
Andrew Lloyd
,
+4 authors
Declan N. C. Jones
Brain research
2007
SB-277011-A is a dopamine D(3) receptor antagonist that exhibits over 100-fold selectivity over dopamine D(2) receptors and a…Â
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2005
2005
The selective dopamine D3 receptor antagonist SB-277011-A attenuates ethanol consumption in ethanol preferring (P) and non-preferring (NP) rats.
Panayotis K. Thanos
,
John M Katana
,
+4 authors
Nora D. Volkow
Pharmacology, biochemistry, and behavior
2005
The mesolimbic dopamine (DA) system plays an important role in mediating addiction to alcohol and other drugs of abuse. Recent…Â
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2004
2004
Selective dopamine D(3) receptor antagonist SB-277011-A potentiates phMRI response to acute amphetamine challenge in the rat brain.
Adam J. Schwarz
,
Alessandro Gozzi
,
+5 authors
Angelo Bifone
Synapse
2004
Dopamine (DA) receptors are a major target for drugs employed in the treatment of neuropsychiatric disorders such as…Â
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Highly Cited
2003
Highly Cited
2003
Attenuation of Cue-Controlled Cocaine-Seeking by a Selective D3 Dopamine Receptor Antagonist SB-277011-A
Patricia Di Ciano
,
Rachel J Underwood
,
Jim J. Hagan
,
Barry J. Everitt
Neuropsychopharmacology
2003
Conditioned stimuli (CS) previously paired with drugs of abuse can elicit cravings in humans, relapse to drug use, and can also…Â
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Highly Cited
2002
Highly Cited
2002
Dopamine D3 receptor antagonism inhibits cocaine-seeking and cocaine-enhanced brain reward in rats.
Stanislav R. Vorel
,
Charles R. Ashby
,
+6 authors
Eliot L. Gardner
The Journal of neuroscience : the official…
2002
dopamine D3 receptor is preferentially localized to the mesocorticolimbic dopaminergic system and has been hypothesized to play a…Â
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Review
2001
Review
2001
SB-277011 GlaxoSmithKline.
Gary Remington
,
Sabrina R. Kapur
Current opinion in investigational drugs
2001
It is presumed that GlaxoSmithKline has taken over from SmithKline Beecham in investigating the highly selective dopamine D3…Â
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2001
2001
Pharmacokinetics of the novel, high-affinity and selective dopamine D3 receptor antagonist SB-277011 in rat, dog and monkey: in vitro/in vivo correlation and the role of aldehyde oxidase.
Nicole Austin
,
Samantha J. Baldwin
,
+8 authors
P. Jeffrey
Xenobiotica; the fate of foreign compounds in…
2001
1. In vitro studies with the selective dopamine D3 receptor antagonist SB-277011 were conducted in liver microsomes and…Â
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Highly Cited
2000
Highly Cited
2000
Pharmacological actions of a novel, high-affinity, and selective human dopamine D(3) receptor antagonist, SB-277011-A.
Charlie Reavill
,
Sara Taylor
,
+23 authors
Jim J. Hagan
The Journal of pharmacology and experimental…
2000
SB-277011-A (trans-N-[4-[2-(6-cyano-1,2,3, 4-tetrahydroisoquinolin-2-yl)ethyl]cyclohexyl]-4-quinolininecarboxamide), is a brain…Â
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2000
2000
Design and synthesis of trans-N-[4-[2-(6-cyano-1,2,3, 4-tetrahydroisoquinolin-2-yl)ethyl]cyclohexyl]-4-quinolinecarboxamide (SB-277011): A potent and selective dopamine D(3) receptor antagonist with…
Geoff Stemp
,
Terri Ashmeade
,
+16 authors
M. Wood
Journal of medicinal chemistry
2000
A selective dopamine D(3) receptor antagonist offers the potential for an effective antipsychotic therapy, free of the serious…Â
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