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S 20499

Known as: S-20499 
National Institutes of Health

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alnespirone

Papers overview

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Highly Cited
1999
Highly Cited
1999
Modification of sexual behavior of Long–Evans male rats by drugs acting on the 5-HT1A receptor
1999
1999
Differential Regulation of Somatodendritic Serotonin 5‐HT1A Receptors by 2‐Week Treatments with the Selective Agonists Alnespirone (S‐20499) and 8‐Hydroxy‐2‐(Di‐n‐Propylamino)tetralin
Abstract : Single treatment with the serotonin (5‐hydroxytryptamine) 5‐HT1A receptor agonists 8‐hydroxy‐2‐(di‐n‐propylamino… 
Highly Cited
1997
Highly Cited
1997
The effect of the selective 5‐HT1A agonists alnespirone (S‐20499) and 8‐OH‐DPAT on extracellular 5‐hydroxytryptamine in different regions of rat brain
1 We have examined the effects of the systemic administration of the selective 5‐HT1A agonist alnespirone (S‐20499) on in vivo 5… 
Highly Cited
1997
Highly Cited
1997
An Ethopharmacological Analysis of Selective Activation of 5-HT1A Receptors: The Mouse 5-HT1A Syndrome
1997
1997
[3H]Alnespirone: a novel specific radioligand of 5-HT1A receptors in the rat brain.
1997
1997
Production and characterization of polyclonal anti-S 20499 antibodies: influence of the hapten structure on stereospecificity.
Immunoassays were studied as an alternative to HPLC methods for the stereoselective determination of a chiral drug, S 20499, a… 
1994
1994
Differential induction of 5-HT1A-mediated responses in vivo by three chemically dissimilar 5-HT1A agonists.
In the rat, activation of 5-hydroxytryptamine1A (5-HT1A) receptors causes hypothermia and the 5-HT syndrome. The effects of three… 
1994
1994
Assessment of the benzodiazepine‐like dependence potential in rats of the putative 5‐HT1A agonist anxiolytic S‐20499
The dependence potential of the putative 5-HT1A agonist anxiolytic S-20499 was assessed in rats in a study in which the… 
1994
1994
Anxiolytic-like effects of 5-HT(1A) agonists in drug-naive and in benzodiazepine-experienced rats.
The efficacy of two 5-HT(1A) receptor agonists in drug-naive and benzodiazepine-experienced rats was compared in two animal tests… 
Highly Cited
1993
Highly Cited
1993
Further assessment of the antagonist properties of the novel and selective 5-HT1A receptor ligands (+)-WAY 100 135 and SDZ 216-525.
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