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Climbing behavior induced by apomorphine in mice: a simple test for the study of dopamine receptors in striatum
TLDR
It appears that this stereotyped behavior of mice treated with low doses of apomorphine might represent a convenient mean to assess the stimulation of striatal dopamine receptors in mice. Expand
Chronic stress in pregnant rats: effects on growth rate, anxiety and memory capabilities of the offspring.
TLDR
Female rats were repeatedly stressed for 10 periods of 15 min by the presence of a cat, at the 10th or the 19th gestational day and their long-term memory was altered and they exhibited an aversive behavior relative to wide areas. Expand
Long-term changes in the sensitivity of pre- and postsynaptic dopamine receptors in mouse striatum evidenced by behavioural and biochemical studies
TLDR
The hyposensitivity of DA ‘autoreceptors’, responding to low doses of DA agonists, mediating an inhibition of DA release and, consequently, behavioural effects opposite to those resulting from the stimulation of postsynaptic receptors, may explain the ‘behavioural facilitation’. Expand
Acute Stress in Pregnant Rats Effects on Growth Rate, Learning, and Memory Capabilities of the Offspring
TLDR
When adult, the offspring of stressed mothers exhibited learning and memory impairments in a delayed alternation task as well as in passive avoidance conditioning and the death rate of the young rats was much greater than that in controls. Expand
Dopamine receptor antagonist properties of S 14506, 8-OH-DPAT, raclopride and clozapine in rodents.
TLDR
From these data, it appears that like raclopride, S 14506 displays dopamine antagonist properties by blocking dopamine D2 receptors, however, the psychopharmacological profile of S14506 is closer to that of clozapine than toThat of raclipride, probably as a result of its actions at 5-HT receptors. Expand
Pharmacological characteristics of dopamine receptors involved in the dual effect of dopamine agonists on yawning behaviour in rats.
TLDR
The decreased APO-induced yawning observed concomitantly with increased sniffing in rats with 6-hydroxydopamine-lesioned olfactory tubercles suggests that yawning and sniffing could be mutually exclusive. Expand
Agomelatine(S 20098) antagonizes the penile erections induced by the stimulation of 5-HT2C receptors in Wistar rats
TLDR
Data suggested that the reported effects were not due to the stimulation of melatonin receptors and that, contrary to melatonin, agomelatine exerted 5-HT2C receptor antagonist properties in addition to its agonist activity atmelatonin receptors. Expand
Structure-affinity relationships of halogenated predicentrine and glaucine derivatives at D1 and D2 dopaminergic receptors: halogenation and D1 receptor selectivity.
TLDR
Results suggest that the 2-hydroxy group on the aporphine skeleton may determine a binding mode favoring D(1)-like over D(2)-like receptors, with enhanced affinity when the C-3 position is halogenated. Expand
Rapid and dissociated changes in sensitivities of different dopamine receptors in mouse brain
TLDR
There is considerable theoretical as well as therapeutical interest in defining specific characteristics of different dopaminergic systems participating in the control of these various functions. Expand
High-affinity [3H]GBR 12783 binding to a specific site associated with the neuronal dopamine uptake complex in the central nervous system.
TLDR
Three-H]GBR 12783 appears an attractive tool for the selective characterization of the dopamine uptake system in vitro and was inhibited by dopamine uptake inhibitors with IC50 highly correlated with their IC50 for inhibiting [3H]dopamine uptake by a rat striatal synaptosomal preparation. Expand
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