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Ribosome Subunits, Large

Known as: Subunits, Large Ribosome, Large Ribosome Subunit, Ribosomal Subunit, Large 
The largest ribonucleoprotein component of RIBOSOMES. It contains the domains which catalyze formation of the peptide bond and translocation of the… 
National Institutes of Health

Related topics

Related topics

7 relations
MicrobiologicalProcess of secretionaspects of radiation effectsphysiological aspects

Narrower (3)

cytosolic large ribosomal subunitmitochondrial large ribosomal subunitorganellar large ribosomal subunit

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Structure of the large ribosomal subunit from human mitochondria
Making mitochondrial hydrophobic proteins Mitochondria produce chemical energy for the cell. Human mitochondria have their own… 
Highly Cited
2007
Highly Cited
2007
Structural basis for aminoglycoside inhibition of bacterial ribosome recycling
Aminoglycosides are widely used antibiotics that cause messenger RNA decoding errors, block mRNA and transfer RNA translocation… 
Highly Cited
2004
Highly Cited
2004
The roles of ribosomal proteins in the structure assembly, and evolution of the large ribosomal subunit.
Highly Cited
2003
Highly Cited
2003
Structures of five antibiotics bound at the peptidyl transferase center of the large ribosomal subunit.
Review
2003
Review
2003
RNA, the first macromolecular catalyst: the ribosome is a ribozyme.
Highly Cited
2000
Highly Cited
2000
Cell Cycle–Regulated Modification of the Ribosome by a Variant Multiubiquitin Chain
Highly Cited
1997
Highly Cited
1997
Database on the structure of large ribosomal subunit RNA
The latest release of the large ribosomal subunit RNA database contains 429 sequences. All these sequences are aligned, and… 
Highly Cited
1982
Highly Cited
1982
Secretory protein translocation across membranes—the role of the ‘docking protein’
On emergence of the signal sequence of nascent secretory proteins from the large ribosomal subunit, translation is stopped by a… 
Highly Cited
1981
Highly Cited
1981
Translocation of proteins across the endoplasmic reticulum III. Signal recognition protein (SRP) causes signal sequence-dependent and site- specific arrest of chain elongation that is released by…
The previously observed (Walter, et al. 1981 J. Cell Biol. 91:545-550) inhibitory effect of SRP selectively on the cell-free… 
Highly Cited
1975
Highly Cited
1975
Transfer to proteins across membranes. II. Reconstitution of functional rough microsomes from heterologous components
The data presented in this paper demonstrate that native small ribosomal subunits from reticulocytes (containing initiation… 
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