Reprogram

Macrophages are not only essential components of innate immunity that contribute to host defense against infections, but also… (More)

Metastatic tumors are the cause of more than 90% of cancer related deaths. Metastasis formation can be considered as a… (More)

Pancreatic ductal adenocarcinoma is on pace to become the second leading cause of cancer-related death. The high mortality rate… (More)

Epigenetic and metabolic alterations in cancer cells are highly intertwined. Oncogene-driven metabolic rewiring modifies the… (More)

A growing number of findings highlight the crucial role of metabolic reprogramming in macrophage activation. Metabolic pathways… (More)

The hallmarks of cancer comprise six biological capabilities acquired during the multistep development of human tumors. The… (More)

Transgenic expression of just four defined transcription factors (c-Myc, Klf4, Oct4 and Sox2) is sufficient to reprogram somatic… (More)

Differentiated cells can be reprogrammed to an embryonic-like state by transfer of nuclear contents into oocytes or by fusion… (More)

Microenvironments appear important in stem cell lineage specification but can be difficult to adequately characterize or control… (More)

NF-kappaB (nuclear factor-kappaB) is a collective name for inducible dimeric transcription factors composed of members of the Rel… (More)