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Silencing of Smed-βcatenin1 generates radial-like hypercephalized planarians
Little is known about the molecular mechanisms responsible for axis establishment during non-embryonic processes such as regeneration and homeostasis. To address this issue, we set out to analyze theExpand
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The BMP pathway is essential for re-specification and maintenance of the dorsoventral axis in regenerating and intact planarians.
The bone morphogenetic protein (BMP) pathway has been shown to play an important role in the establishment of the dorsoventral axis during development in both vertebrate and invertebrate species. InExpand
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Smed-Evi/Wntless is required for β-catenin-dependent and -independent processes during planarian regeneration
Planarians can regenerate a whole animal from only a small piece of their body, and have become an important model for stem cell biology. To identify regenerative processes dependent on Wnt growthExpand
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The power of regeneration and the stem-cell kingdom: freshwater planarians (Platyhelminthes).
  • E. Saló
  • Biology, Medicine
  • BioEssays : news and reviews in molecular…
  • 1 May 2006
The great powers of regeneration shown by freshwater planarians, capable of regenerating a complete organism from any tiny body fragment, have attracted the interest of scientists throughout history.Expand
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Regeneration and pattern formation in planarians. I. The pattern of mitosis in anterior and posterior regeneration in Dugesia (G) tigrina, and a new proposal for blastema formation.
  • E. Saló, J. Baguñá
  • Biology, Medicine
  • Journal of embryology and experimental morphology
  • 1 October 1984
Mitotic activity during regeneration in the planarian Dugesia (G) tigrina shows a biphasic pattern, with a first maximum at 4-12 h, a second and higher maximum at 2-4 days, and a relative minimum inExpand
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Searching for the prototypic eye genetic network: Sine oculis is essential for eye regeneration in planarians.
We have identified a sine oculis gene in the planarian Girardia tigrina (Platyhelminthes; Turbellaria; Tricladida). The planarian sine oculis gene (Gtso) encodes a protein with a sine oculis (Six)Expand
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The genetic network of prototypic planarian eye regeneration is Pax6 independent.
We report the presence of two Pax6-related genes, Pax6A and Pax6B, which are highly conserved in two planarian species Dugesia japonica and Girardia tigrina (Platyhelminthes, Tricladida). Pax6A isExpand
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Regeneration and pattern formation in planarians. III. that neoblasts are totipotent stem cells and the cells
In most regenerating systems, blastema cells arise by dedifferentiation of functional tissue cells. In is still debatable whether dedifferentiated cells or a undifferentiated cells, the neoblasts,Expand
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The planarian nanos-like gene Smednos is expressed in germline and eye precursor cells during development and regeneration
Planarians are highly regenerative organisms with the ability to remake all their cell types, including the germ cells. The germ cells have been suggested to arise from totipotent neoblasts throughExpand
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Noggin and Noggin-Like Genes Control Dorsoventral Axis Regeneration in Planarians
Planarians regenerate a whole animal from a small body piece within a few days. Recent studies have shown that the bone morphogenetic protein (BMP) pathway is required to reestablish the dorsoventralExpand
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