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Regulator of G-Protein Signaling 4
Known as:
RGP4
, RGS4
Regulator of G-protein signaling 4 (205 aa, ~23 kDa) is encoded by the human RGS4 gene. This protein is involved in the promotion of GTPase activity.
National Institutes of Health
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Related topics
Related topics
8 relations
G Protein-Coupled Receptor Signaling
Ligand Binding
RGS Domain
RGS4 gene
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Mapping the regulator of G protein signaling 4 (RGS4): presynaptic and postsynaptic substrates for neuroregulation in prefrontal cortex.
C. Paspalas
,
L. Selemon
,
A. Arnsten
Cerebral Cortex
2009
Corpus ID: 11073619
Regulator of G protein signaling 4 (RGS4) regulates intracellular signaling via G proteins and is markedly reduced in the…
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2007
2007
Regulator of G-Protein Signaling 4 Interacts with Metabotropic Glutamate Receptor Subtype 5 in Rat Striatum: Relevance to Amphetamine Behavioral Sensitization
M. Schwendt
,
J. McGinty
Journal of Pharmacology and Experimental…
2007
Corpus ID: 16300901
Regulator of G-protein signaling (RGS) 4 negatively modulates signaling of several Gαq-coupled receptors, including metabotropic…
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Highly Cited
2006
Highly Cited
2006
Selective interactions between G protein subunits and RGS4 with the C-terminal domains of the mu- and delta-opioid receptors regulate opioid receptor signaling.
Z. Georgoussi
,
Leonidas J. Leontiadis
,
Georgia Mazarakou
,
M. Merkouris
,
Karren Hyde
,
H. Hamm
Cellular Signalling
2006
Corpus ID: 20805733
2006
2006
Cellular stress increases RGS2 mRNA and decreases RGS4 mRNA levels in SH-SY5Y cells
Ling Song
,
R. Jope
Neuroscience Letters
2006
Corpus ID: 37747641
Highly Cited
2004
Highly Cited
2004
Differentially Regulated Expression of Endogenous RGS4 and RGS7*
A. Krumins
,
S. A. Barker
,
+5 authors
S. Mumby
Journal of Biological Chemistry
2004
Corpus ID: 29283202
Regulators of G protein signaling (RGS proteins) constitute a family of newly appreciated components of G protein-mediated signal…
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2003
2003
Regulators of G-protein Signaling (RGS) 4, Insertion into Model Membranes and Inhibition of Activity by Phosphatidic Acid*
Y. Ouyang
,
Y. Tu
,
S. A. Barker
,
Fu-yu Yang
Journal of Biological Chemistry
2003
Corpus ID: 5520596
Regulators of G-protein signaling (RGS) proteins are critical for attenuating G protein-coupled signaling pathways. The membrane…
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2000
2000
NMR structure of free RGS4 reveals an induced conformational change upon binding Galpha.
F. Moy
,
Pranab K. Chanda
,
+5 authors
Robert Powers
Biochemistry
2000
Corpus ID: 18136347
Heterotrimeric guanine nucleotide-binding proteins (G-proteins) are transducers in many cellular transmembrane signaling systems…
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2000
2000
Rapid kinetics of regulator of G-protein signaling (RGS)-mediated Galphai and Galphao deactivation. Galpha specificity of RGS4 AND RGS7.
K. Lan
,
H. Zhong
,
M. Nanamori
,
R. Neubig
Journal of Biological Chemistry
2000
Corpus ID: 33704764
Regulator of G-protein signaling (RGS) proteins accelerate GTP hydrolysis by Galpha subunits speeding deactivation. Galpha…
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Highly Cited
1999
Highly Cited
1999
Solution structure of human GAIP (Galpha interacting protein): a regulator of G protein signaling.
Eva de Alba
,
Luc De Vries
,
M. Farquhar
,
Nico Tjandra
Journal of Molecular Biology
1999
Corpus ID: 32983777
The solution structure of the human protein GAIP (Galpha interacting protein), a regulator of G protein signaling, has been…
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1998
1998
Mutational Analysis of the Asn Residue Essential for RGS Protein Binding to G-proteins*
M. Natochin
,
R. McEntaffer
,
N. Artemyev
Journal of Biological Chemistry
1998
Corpus ID: 26489458
Members of the RGS family serve as GTPase-activating proteins (GAPs) for heterotrimeric G-proteins and negatively regulate…
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