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Recombinant Interleukin-1

Known as: Lymphocyte-Stimulating Hormone, Interleukin-1, Interleukin 1 
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine interleukin-1 (IL-1). Produced mainly by… 
National Institutes of Health

Related topics

Related topics

6 relations
Inhibition of Cell ProliferationInterleukin 1 MeasurementInterleukin-1 alphaInterleukin-1 beta

Broader (1)

Interleukin-1

Papers overview

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Review
2004
Review
2004
Protective effects of lactoferrin in Escherichia coli-induced bacteremia in mice: Relationship to reduced serum TNF alpha level and increased turnover of neutrophils
AbstractObjective and Design:Previous studies demonstrated that lactoferrin (LF), given intravenously (i.v.), 24 h before lethal… 
Highly Cited
1990
Highly Cited
1990
Proliferation of early human myeloid precursors induced by interleukin-1 and recombinant soluble CD23.
Low affinity Fc epsilon receptors (Fc epsilon RII/CD23) or their soluble fragments have various biologic effects on B- and T-cell… 
Highly Cited
1989
Highly Cited
1989
The role monokines in granuloma formation in mice: The ability of interleukin 1 and tumor necrosis factor-α to induce lung granulomas
Highly Cited
1988
Highly Cited
1988
Effect of maximal physical exercise on T-lymphocyte subpopulations and on interleukin 1 (IL 1) and interleukin 2 (IL 2) production in vitro.
Maximal physical exercise was performed on a Monark bicycle ergometer according to individual schemes. The investigations were… 
Highly Cited
1988
Highly Cited
1988
Protection of neutropenic mice from lethal Candida albicans infection by recombinant interleukin 1
Natural and synthetic immunomodulators that increase nonspecific resistance to infection are also known to induce interleukin 1… 
1988
1988
Human recombinant interleukin‐1α‐mediated stimulation of procollagenase production and suppression of biosynthesis of tissue inhibitor of metalloproteinases in rabbit uterine cervical fibroblasts
Highly Cited
1987
Highly Cited
1987
Monoclonal antibodies to human recombinant interleukin 1 (IL 1)beta: quantitation of IL 1 beta and inhibition of biological activity.
Monoclonal antibodies (McAb) were developed to the Mr 17,500 form of human recombinant interleukin 1, IL 1 beta. Four McAb have… 
Highly Cited
1987
Highly Cited
1987
Circulating interleukin 1 and tumor necrosis factor during inflammation.
It is proposed that interleukin 1 (IL 1) and tumor necrosis factor (TNF) alpha play central roles in the host's response to… 
Highly Cited
1986
Highly Cited
1986
Decreased serum interleukin 1 activity and monocyte interleukin 1 production in patients with fatal sepsis
The role of interleukin 1 (IL 1) in 16 patients with sepsis and 16 normal controls was investigated. Thymocyte costimulation was… 
Highly Cited
1985
Highly Cited
1985
Human monocyte heterogeneity: Interleukin 1 and prostaglandin E2 production by separate subsets
Human peripheral blood monocytes were separated into four different subpopula‐tions by means of a discontinuous bovine serum… 
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