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Recombinant Interleukin-1

Known as: Lymphocyte-Stimulating Hormone, Interleukin-1, Interleukin 1 
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine interleukin-1 (IL-1). Produced mainly by… Expand
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
OBJECTIVE To examine the therapeutic effect of the interleukin 1 (IL1) receptor antagonist anakinra in ankylosing spondylitis in… Expand
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Highly Cited
1999
Highly Cited
1999
The zinc finger protein A20 is a tumor necrosis factor (TNF)– and interleukin 1 (IL-1)-inducible protein that negatively… Expand
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Highly Cited
1992
Highly Cited
1992
OBJECTIVES Interleukin-1 has been implicated in the mechanisms responsible for preterm parturition in the setting of intrauterine… Expand
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Highly Cited
1991
Highly Cited
1991
Rats received various doses of interleukin 1 (IL-1) (range, 0.5-25.0 ng) or pyrogen-free saline intracerebroventricularly during… Expand
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Highly Cited
1989
Highly Cited
1989
We have analyzed the modulation of amyloid beta-protein precursor (APP) gene expression in human umbilical vein endothelial cells… Expand
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Highly Cited
1988
Highly Cited
1988
Human monocytes produce a number of soluble mediators involved in regulation of inflammation and lymphocyte growth and… Expand
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Highly Cited
1986
Highly Cited
1986
Pretreatment with recombinant interleukin 1 (IL 1) protects mice in a dose-dependent manner from lethal effects of ionizing… Expand
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Highly Cited
1986
Highly Cited
1986
We examined the role of the neutrophil membrane antigen complex designated CDw18 (LFA-1/Mac-1/p150, 95) in human peripheral blood… Expand
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Highly Cited
1986
Highly Cited
1986
Complementary DNA coding for human monocyte interleukin 1 (IL-1), pI 7 form, was expressed in Escherichia coli. During… Expand
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Highly Cited
1985
Highly Cited
1985
During the acute phase response to tissue injury or inflammation, the concentration of several plasma proteins change. Previous… Expand
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