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Interleukin-1 beta

Known as: Interleukin-1beta, beta interleukin-1, Interleukin 1, Beta 
An interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein. Proteolytic processing of the precursor form by CASPASE 1… Expand
National Institutes of Health

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Alzheimer's Disease Pathway KEGGApoptosisCell Differentiation processCell Proliferation
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Broader (1)

Interleukin-1

Papers overview

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Review
2017
Review
2017
Interleukin-1 Beta as a Target for Atherosclerosis Therapy: Biological Basis of CANTOS and Beyond.
  • Peter Libby
  • Journal of the American College of Cardiology
  • 2017
    • Corpus ID: 205594583
Inflammatory pathways drive atherogenesis and link conventional risk factors to atherosclerosis and its complications. One… Expand
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Review
2017
Review
2017
Peripheral Alterations in Cytokine and Chemokine Levels After Antidepressant Drug Treatment for Major Depressive Disorder: Systematic Review and Meta-Analysis
Mounting evidence suggests that aberrations in immune-inflammatory pathways contribute to the pathophysiology of major depressive… Expand
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Review
2009
Review
2009
Immunological and inflammatory functions of the interleukin-1 family.
More than any other cytokine family, the interleukin (IL)-1 family is closely linked to the innate immune response. This linkage… Expand
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Highly Cited
2009
Highly Cited
2009
Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity.
Th17 cells, CD4(+) T cells that secrete interleukin-17 (IL-17), are pathogenic in autoimmune diseases and their development and… Expand
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Highly Cited
2007
Highly Cited
2007
Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells.
Interleukin 17 (IL-17)-producing CD4(+) helper T cells (T(H)-17 cells) have been linked to host defense and autoimmune diseases… Expand
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Highly Cited
2007
Highly Cited
2007
Interleukin-1-receptor antagonist in type 2 diabetes mellitus.
BACKGROUND The expression of interleukin-1-receptor antagonist is reduced in pancreatic islets of patients with type 2 diabetes… Expand
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Highly Cited
2006
Highly Cited
2006
Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor.
P2X(7) receptors are ATP-gated cation channels; their activation in macrophage also leads to rapid opening of a membrane pore… Expand
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Highly Cited
2000
Highly Cited
2000
Interleukin-1 polymorphisms associated with increased risk of gastric cancer
Helicobacter pylori infection is associated with a variety of clinical outcomes including gastric cancer and duodenal ulcer… Expand
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Highly Cited
1995
Highly Cited
1995
Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme.
The interleukin-1 beta (IL-1 beta) converting enzyme (ICE) processes the inactive IL-1 beta precursor to the proinflammatory… Expand
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Highly Cited
1994
Highly Cited
1994
CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme.
We have cloned a novel apoptotic gene from human Jurkat T-lymphocytes. The new gene encodes a 32-kDa putative cysteine protease… Expand
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