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Interleukin-1 beta
Known as:
Interleukin-1beta
, beta interleukin-1
, Interleukin 1, Beta
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An interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein. Proteolytic processing of the precursor form by CASPASE 1…
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National Institutes of Health
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Related topics
Related topics
40 relations
Alzheimer's Disease Pathway KEGG
Apoptosis
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Cell Proliferation
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Broader (1)
Interleukin-1
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
The Inflammasomes
K. Schroder
,
J. Tschopp
Cell
2010
Corpus ID: 16916572
Review
2009
Review
2009
Immunological and inflammatory functions of the interleukin-1 family.
C. Dinarello
Annual review of immunology
2009
Corpus ID: 25017800
More than any other cytokine family, the interleukin (IL)-1 family is closely linked to the innate immune response. This linkage…
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Highly Cited
2008
Highly Cited
2008
Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
H. Sokol
,
B. Pigneur
,
+17 authors
P. Langella
Proceedings of the National Academy of Sciences
2008
Corpus ID: 266737
A decrease in the abundance and biodiversity of intestinal bacteria within the dominant phylum Firmicutes has been observed…
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Highly Cited
2006
Highly Cited
2006
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells.
M. Veldhoen
,
R. J. Hocking
,
C. Atkins
,
R. Locksley
,
B. Stockinger
Immunity
2006
Corpus ID: 20446745
Highly Cited
2000
Highly Cited
2000
Interleukin-1 polymorphisms associated with increased risk of gastric cancer
E. El-Omar
,
M. Carrington
,
+11 authors
C. Rabkin
Nature
2000
Corpus ID: 1288472
Helicobacter pylori infection is associated with a variety of clinical outcomes including gastric cancer and duodenal ulcer…
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Review
1996
Review
1996
Biologic basis for interleukin-1 in disease.
C. Dinarello
Blood
1996
Corpus ID: 22980407
To understand the role of the proinflammatory cytokine interleukin-1 (IL-1) in disease, investigators have studied how production…
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Highly Cited
1995
Highly Cited
1995
Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme.
K. Kuida
,
J. Lippke
,
+4 authors
R. Flavell
Science
1995
Corpus ID: 44773115
The interleukin-1 beta (IL-1 beta) converting enzyme (ICE) processes the inactive IL-1 beta precursor to the proinflammatory…
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Highly Cited
1995
Highly Cited
1995
FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis
A. Chinnaiyan
,
K. O'rourke
,
M. Tewari
,
V. Dixit
Cell
1995
Corpus ID: 16906755
Highly Cited
1992
Highly Cited
1992
Molecular cloning of the interleukin-1 beta converting enzyme.
D. Cerretti
,
C. Kozlosky
,
+7 authors
L. Cannizzaro
Science
1992
Corpus ID: 34882457
Interleukin-1 beta (IL-1 beta) mediates a wide range of immune and inflammatory responses. The active cytokine is generated by…
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Highly Cited
1990
Highly Cited
1990
A novel secretory pathway for interleukin‐1 beta, a protein lacking a signal sequence.
A. Rubartelli
,
F. Cozzolino
,
M. Talio
,
R. Sitia
The EMBO journal
1990
Corpus ID: 8539595
Interleukin 1 (IL‐1) is a major soluble mediator of inflammation. Two human IL‐1 genes, alpha and beta, have been isolated, which…
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