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Interleukin-1 beta

Known as: Interleukin-1beta, beta interleukin-1, Interleukin 1, Beta 
An interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein. Proteolytic processing of the precursor form by CASPASE 1… 
National Institutes of Health

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Interleukin-1

Papers overview

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Review
2010
Review
2010
The Inflammasomes
Review
2009
Review
2009
Immunological and inflammatory functions of the interleukin-1 family.
  • C. Dinarello
  • Annual review of immunology
  • 2009
  • Corpus ID: 25017800
More than any other cytokine family, the interleukin (IL)-1 family is closely linked to the innate immune response. This linkage… 
Highly Cited
2008
Highly Cited
2008
Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
A decrease in the abundance and biodiversity of intestinal bacteria within the dominant phylum Firmicutes has been observed… 
Highly Cited
2006
Highly Cited
2006
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells.
Highly Cited
2000
Highly Cited
2000
Interleukin-1 polymorphisms associated with increased risk of gastric cancer
Helicobacter pylori infection is associated with a variety of clinical outcomes including gastric cancer and duodenal ulcer… 
Review
1996
Review
1996
Biologic basis for interleukin-1 in disease.
To understand the role of the proinflammatory cytokine interleukin-1 (IL-1) in disease, investigators have studied how production… 
Highly Cited
1995
Highly Cited
1995
Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme.
The interleukin-1 beta (IL-1 beta) converting enzyme (ICE) processes the inactive IL-1 beta precursor to the proinflammatory… 
Highly Cited
1995
Highly Cited
1995
FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis
Highly Cited
1992
Highly Cited
1992
Molecular cloning of the interleukin-1 beta converting enzyme.
Interleukin-1 beta (IL-1 beta) mediates a wide range of immune and inflammatory responses. The active cytokine is generated by… 
Highly Cited
1990
Highly Cited
1990
A novel secretory pathway for interleukin‐1 beta, a protein lacking a signal sequence.
Interleukin 1 (IL‐1) is a major soluble mediator of inflammation. Two human IL‐1 genes, alpha and beta, have been isolated, which… 
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