Interleukin-1 beta

Known as: Interleukin-1beta, beta interleukin-1, Interleukin 1, Beta 
An interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein. Proteolytic processing of the precursor form by CASPASE 1… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1980-2018
05001000150019802018

Papers overview

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Highly Cited
2009
Highly Cited
2009
Th17 cells, CD4(+) T cells that secrete interleukin-17 (IL-17), are pathogenic in autoimmune diseases and their development and… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND The expression of interleukin-1-receptor antagonist is reduced in pancreatic islets of patients with type 2 diabetes… (More)
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Highly Cited
2006
Highly Cited
2006
It was recently demonstrated that interleukin (IL)-23-driven IL-17-producing (ThIL-17) T cells mediate inflammatory pathology in… (More)
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Highly Cited
2000
Highly Cited
2000
Helicobacter pylori infection is associated with a variety of clinical outcomes including gastric cancer and duodenal ulcer… (More)
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Highly Cited
1995
Highly Cited
1995
The interleukin-1 beta (IL-1 beta) converting enzyme (ICE) processes the inactive IL-1 beta precursor to the proinflammatory… (More)
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Highly Cited
1994
Highly Cited
1994
We have cloned a novel apoptotic gene from human Jurkat T-lymphocytes. The new gene encodes a 32-kDa putative cysteine protease… (More)
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Highly Cited
1993
Highly Cited
1993
We have cloned the C. elegans cell death gene ced-3. A ced-3 transcript is most abundant during embryogenesis, the stage during… (More)
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Highly Cited
1992
Highly Cited
1992
Interleukin-1 beta (IL-1 beta) mediates a wide range of immune and inflammatory responses. The active cytokine is generated by… (More)
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Highly Cited
1992
Highly Cited
1992
Cowpox virus effectively inhibits inflammatory responses against viral infection in the chick embryo. This study demonstrates… (More)
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Highly Cited
1992
Highly Cited
1992
In the present study we searched for restriction fragment length polymorphisms (RFLP) in the human interleukin-1 beta (IL-1 beta… (More)
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