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Interleukin-1 beta

Known as: Interleukin-1beta, beta interleukin-1, Interleukin 1, Beta 
An interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein. Proteolytic processing of the precursor form by CASPASE 1… 
National Institutes of Health

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Alzheimer's Disease Pathway KEGGApoptosisCell Differentiation processCell Proliferation

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Interleukin-1

Papers overview

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Highly Cited
2007
Highly Cited
2007
The Interleukin-22/STAT3 Pathway Potentiates Expression of Inducible Nitric-oxide Synthase in Human Colon Carcinoma Cells*
Inducible nitric-oxide synthase (iNOS) has been identified as a marker and mediator of disease in human colonic inflammation and… 
Highly Cited
2000
Highly Cited
2000
Distinct patterns of stimulus‐inducible chemokine mRNA accumulation in human fetal astrocytes and microglia
Interferon‐γ‐inducible 10 kd protein (IP‐10) is an ELR (Glu‐Leu‐Arg)− α chemokine with known chemotactic effects on T cells and… 
Highly Cited
1999
Highly Cited
1999
Immunohistochemical localization of interleukin-1β, interleukin-1 receptor antagonist and interleukin-1β converting enzyme/caspase-1 in the rat brain after peripheral administration of kainic acid
Highly Cited
1997
Highly Cited
1997
Constitutive intra-articular expression of human IL-1 beta following gene transfer to rabbit synovium produces all major pathologies of human rheumatoid arthritis.
To investigate the pathophysiologic effects of chronically elevated intra-articular levels of IL-1 beta, we used an ex vivo gene… 
Highly Cited
1997
Highly Cited
1997
Prevention by anti-LFA-1 of acute myoblast death following transplantation.
Myoblast transplantation is a potential treatment for Duchenne muscular dystrophy. One of the problems possibly responsible for… 
Highly Cited
1993
Highly Cited
1993
Kinetics of folding of the all-beta sheet protein interleukin-1 beta.
The folding of the all-beta sheet protein, interleukin-1 beta, was studied with nuclear magnetic resonance (NMR) spectroscopy… 
Highly Cited
1992
Highly Cited
1992
Interleukin‐1β induces the expression of an isoform of nitric oxide synthase in insulin‐producing cells, which is similar to that observed in activated macrophages
Highly Cited
1991
Highly Cited
1991
Regulation of integrin-type cell adhesion receptors by cytokines.
Highly Cited
1990
Highly Cited
1990
Recombinant C5a stimulates transcription rather than translation of interleukin-1 (IL-1) and tumor necrosis factor: translational signal provided by lipopolysaccharide or IL-1 itself.
We investigated the effects of recombinant C5a (rC5a) on gene expression and synthesis of interleukin-1 beta (IL-1 beta) and… 
Highly Cited
1988
Highly Cited
1988
Association between HLA‐DR2 and Production of Tumour Necrosis Factor α and Interleukin 1 by Mononuclear Cells Activated by Lipopolysaccharide
The production of tumour necrosis factor (TNF) and interleukin 1 (IL‐1) by lipopolysaccharide‐activated mononuclear cells from 39… 
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