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Receptors, Purinergic P2

Known as: Purinoceptors, P2, P2 Purinoceptor, P2 Purinoceptors 
A class of cell surface receptors for PURINES that prefer ATP or ADP over ADENOSINE. P2 purinergic receptors are widespread in the periphery and in… 
National Institutes of Health

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Narrower (8)

ATP ReceptorsP2Y13 protein, ratReceptors, ADPpurinoceptor P2X1
In Bloodaspects of radiation effectsphysiological aspects

Papers overview

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Highly Cited
2008
Highly Cited
2008
Possible involvement of P2X7 receptor activation in microglial neuroprotection against focal cerebral ischemia in rats.
Microglia play important roles in the pathogenic cascade following cerebral ischemia, since they express growth factors… 
Highly Cited
2003
Highly Cited
2003
Stimulation of P2 purinergic receptors induces the release of eosinophil cationic protein and interleukin‐8 from human eosinophils
Extracellular nucleotides are the focus of increasing attention for their role as extracellular mediators since they are released… 
Highly Cited
1999
Highly Cited
1999
Chemotaxis of rat mast cells toward adenine nucleotides.
Rat mucosal mast cells express P2 purinoceptors, occupation of which mobilizes cytosolic Ca2+ and activates a potassium… 
Highly Cited
1999
Highly Cited
1999
Potentiation of ATP calcium responses by A2B receptor stimulation and other signals coupled to Gs proteins in type‐1 cerebellar astrocytes
We have studied the interaction between P1 and P2 purinoceptors in purified type‐1 astrocyte cultures from postnatal days 7–8 rat… 
Highly Cited
1999
Highly Cited
1999
Functional heterogeneity of endothelial P2 purinoceptors in the cerebrovascular tree of the rat.
The effects of stimulating P2Y1 or P2Y2 purinoceptors on the endothelium of isolated middle cerebral arteries (MCAs), third-order… 
Highly Cited
1999
Highly Cited
1999
Purinergic regulation of cation conductances and intracellular Ca2+ in cultured rat retinal pigment epithelial cells
1 We used whole‐cell patch clamp and fluorescent calcium imaging techniques to investigate the effects of adenosine 5… 
1998
1998
Ca2+ mobilization in bovine corneal endothelial cells by P2 purinergic receptors.
PURPOSE To characterize Ca2+ mobilization by P2 receptors in the bovine corneal endothelial cells (BCEC). METHODS Changes in… 
Highly Cited
1996
Highly Cited
1996
The possible role of ATP and PACAP as mediators of apamin‐sensitive NANC inhibitory junction potentials in circular muscle of guinea‐pig colon
1 In the presence of atropine (1 μm), guanethidine (3 μm), indomethacin (3 μm), nifedipine (1 μm), L‐nitroarginine (L‐NOARG, 100… 
Highly Cited
1985
Highly Cited
1985
Further evidence for involvement of adenosine-5'-triphosphate in non-adrenergic non-cholinergic relaxation of the isolated rat duodenum.
Highly Cited
1981
Highly Cited
1981
EVIDENCE IN SUPPORT OF THE P1/P2 PURINOCEPTOR HYPOTHESIS IN THE GUINEA‐PIG TAENIA COLI
1 The relaxations induced by adenosine 5′‐triphosphate (ATP), adenosine 5′‐diphosphate (ADP), adenosine 5′‐monophosphate (AMP… 
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