Receptors, Purinergic P2

Known as: Purinoceptors, P2, P2 Purinoceptor, P2 Purinoceptors 
A class of cell surface receptors for PURINES that prefer ATP or ADP over ADENOSINE. P2 purinergic receptors are widespread in the periphery and in… (More)
National Institutes of Health

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ATP ReceptorsP2Y13 protein, ratReceptors, ADPpurinoceptor P2X1
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In Bloodaspects of radiation effectsphysiological aspects

Papers overview

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Review
2010
Review
2010
Pain and purinergic signaling
A growing body of evidence indicates that extracellular nucleotides play important roles in the regulation of neuronal and glial… (More)
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Review
2008
Review
2008
Purinergic systems in microglia
Accumulating findings indicate that nucleotides play an important role in microglia through P2 purinoceptors. P2 purinoceptors… (More)
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Review
2007
Review
2007
Interaction of P2 purinergic receptors with cellular macromolecules
Ionotropic P2X and metabotropic P2Y receptors interact with a number of macromolecules in the cell membrane which may contribute… (More)
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Highly Cited
2003
Highly Cited
2003
Activation of extracellular signal-regulated kinase by stretch-induced injury in astrocytes involves extracellular ATP and P2 purinergic receptors.
Gliosis is characterized by hypertrophic and hyperplastic responses of astrocytes to brain injury. To determine whether injury of… (More)
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Highly Cited
2000
Highly Cited
2000
The P2 purinergic receptors of human dendritic cells: identification and coupling to cytokine release.
We investigated the expression of purinoceptors in human dendritic cells, providing functional, pharmacological, and biochemical… (More)
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Highly Cited
1999
Highly Cited
1999
Nucleotides regulate NaCl transport in mIMCD-K2 cells via P2X and P2Y purinergic receptors.
Extracellular nucleotides regulate NaCl transport in some epithelia. However, the effects of nucleotide agonists on NaCl… (More)
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Highly Cited
1999
Highly Cited
1999
Mouse dendritic cells express the P2X7 purinergic receptor: characterization and possible participation in antigen presentation.
Immune cells express P2 purinoceptors of the P2Y and P2X subtypes. In the present work, we show that three dendritic cell (DC… (More)
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1998
1998
Mitogenic signaling from P1 and P2 purinergic receptors to mitogen-activated protein kinase in human fetal astrocyte cultures
To investigate potential trophic actions of extracellular ATP in human astrocytes, we have examined mitogenic signaling by… (More)
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Highly Cited
1992
Highly Cited
1992
PPADS, a novel functionally selective antagonist of P2 purinoceptor-mediated responses.
We have characterized PPADS (pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid) as a novel antagonist which selectively blocks… (More)
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1976
1976
Purinergic Receptors
The term purinergic receptor (or purinoceptor) was first introduced to describe classes of membrane receptors that, when… (More)
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