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Receptors, Purinergic P2

Known as: Purinoceptors, P2, P2 Purinoceptor, P2 Purinoceptors 
A class of cell surface receptors for PURINES that prefer ATP or ADP over ADENOSINE. P2 purinergic receptors are widespread in the periphery and in… Expand
National Institutes of Health

Related topics

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11 relations

Narrower (8)

ATP ReceptorsP2Y13 protein, ratReceptors, ADPpurinoceptor P2X1
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In Bloodaspects of radiation effectsphysiological aspects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Extracellular ATP and P2 purinergic signalling in the tumour microenvironment
Modulation of the biochemical composition of the tumour microenvironment is a new frontier of cancer therapy. Several… Expand
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Highly Cited
2003
Highly Cited
2003
Activation of Extracellular Signal-Regulated Kinase by Stretch-Induced Injury in Astrocytes Involves Extracellular ATP and P2 Purinergic Receptors
Gliosis is characterized by hypertrophic and hyperplastic responses of astrocytes to brain injury. To determine whether injury of… Expand
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Review
2002
Review
2002
P2Y and P2X purinoceptor mediated Ca2+ signalling in glial cell pathology in the central nervous system.
Activation of purinoceptors by extracellular ATP is an important component of the glial response to injury in the central nervous… Expand
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Highly Cited
2000
Highly Cited
2000
The P2 purinergic receptors of human dendritic cells: identification and coupling to cytokine release
We investigated the expression of purinoceptors in human dendritic cells, providing functional, pharmacological, and biochemical… Expand
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Highly Cited
1997
Highly Cited
1997
Towards a revised nomenclature for P1 and P2 receptors.
The classification of receptors for adenosine, ATP and ADP (collectively called purinoceptors) has seen a number of developments… Expand
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Highly Cited
1995
Highly Cited
1995
Pharmacological characterization of heterologously expressed ATP-gated cation channels (P2x purinoceptors).
cDNAs encoding P2x purinoceptors from human bladder smooth muscle and from rat PC-12 cells were expressed in oocytes and human… Expand
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Highly Cited
1995
Highly Cited
1995
Pharmacological selectivity of the cloned human P2U‐purinoceptor: potent activation by diadenosine tetraphosphate
1 The human P2U‐purinoceptor was stably expressed in 1321N1 human astrocytoma cells and the pharmacological selectivity of the… Expand
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Highly Cited
1992
Highly Cited
1992
PPADS, a novel functionally selective antagonist of P2 purinoceptor-mediated responses.
We have characterized PPADS (pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid) as a novel antagonist which selectively blocks… Expand
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Highly Cited
1991
Highly Cited
1991
Regulation of transepithelial ion transport and intracellular calcium by extracellular ATP in human normal and cystic fibrosis airway epithelium
1 The role of extracellular nucleotides in regulation of ion transport activities (short circuit current, Isc) of human… Expand
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Highly Cited
1976
Highly Cited
1976
Purinergic Receptors
The term purinergic receptor (or purinoceptor) was first introduced to describe classes of membrane receptors that, when… Expand
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