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Receptors, CCR4

Known as: CC Chemokine Receptors 4, Antigen, CD194, Antigens, CD194 
CCR receptors with specificity for CHEMOKINE CCL17 and CHEMOKINE CCL22. They are expressed at high levels in T-LYMPHOCYTES; MAST CELLS; DENDRITIC… 
National Institutes of Health

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Related topics

8 relations

Narrower (2)

C-C Chemokine Receptor Type 4, humanCCR4 protein, human
CCR4 geneIn Bloodagonistsantagonists & inhibitors

Papers overview

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Highly Cited
2008
Highly Cited
2008
Aberrant expression of Fra-2 promotes CCR4 expression and cell proliferation in adult T-cell leukemia
Adult T-cell leukemia (ATL) is a mature CD4+ T-cell malignancy etiologically associated with human T-cell leukemia virus type 1… 
Highly Cited
2006
Highly Cited
2006
RANKL-induced CCL22/macrophage-derived chemokine produced from osteoclasts potentially promotes the bone metastasis of lung cancer expressing its receptor CCR4
Chemokines are now known to play an important role in cancer growth and metastasis. Here we report that differentiating… 
Highly Cited
2004
Highly Cited
2004
CXC Chemokine Receptor 3 and CC Chemokine Receptor 4 Expression in T-Cell and NK-Cell Lymphomas with Special Reference to Clinicopathological Significance for Peripheral T-Cell Lymphoma, Unspecified
We recently reported expression of the chemokine receptors CXC chemokine receptor 3 (CXCR3) and CC chemokine receptor 4 (CCR4) in… 
Highly Cited
2004
Highly Cited
2004
The CC Chemokine Receptor 4 as a Novel Specific Molecular Target for Immunotherapy in Adult T-Cell Leukemia/Lymphoma
Adult T-cell leukemia/lymphoma (ATLL) is a peripheral T-cell neoplasm with dismal prognosis, and no optimal therapy has been… 
Highly Cited
2003
Highly Cited
2003
CCR4 blockade does not inhibit allergic airways inflammation
The CC chemokine receptor 4 (CCR4) shows selectivity for the recruitment of memory T cell subsets, including those of the T… 
Highly Cited
2002
Highly Cited
2002
Presence of high contents of thymus and activation-regulated chemokine in platelets and elevated plasma levels of thymus and activation-regulated chemokine and macrophage-derived chemokine in…
BACKGROUND T(H)2 cells and eosinophils selectively express CC chemokine receptor 4 and CCR3, respectively, and their chemokine… 
Highly Cited
2001
Highly Cited
2001
Macrophage-derived chemokine (MDC/CCL22) and CCR4 are involved in the formation of T lymphocyte-dendritic cell clusters in human inflamed skin and secondary lymphoid tissue.
Highly Cited
2001
Highly Cited
2001
The CC chemokines MDC and TARC induce platelet activation via CCR4.
Highly Cited
1999
Highly Cited
1999
Macrophage-derived chemokine induces human eosinophil chemotaxis in a CC chemokine receptor 3- and CC chemokine receptor 4-independent manner.
Highly Cited
1998
Highly Cited
1998
Macrophage-derived Chemokine Is a Functional Ligand for the CC Chemokine Receptor 4*
Macrophage-derived chemokine (MDC) is a recently identified member of the CC chemokine family. MDC is not closely related to… 
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