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Receptors, CCR4

Known as: CC Chemokine Receptors 4, Antigen, CD194, Antigens, CD194 
CCR receptors with specificity for CHEMOKINE CCL17 and CHEMOKINE CCL22. They are expressed at high levels in T-LYMPHOCYTES; MAST CELLS; DENDRITIC… 
National Institutes of Health

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C-C Chemokine Receptor Type 4, humanCCR4 protein, human
CCR4 geneIn Bloodagonistsantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
CCR4 antagonist (C021) influences the level of nociceptive factors and enhances the analgesic potency of morphine in a rat model of neuropathic pain.
2016
2016
Administration of an anti-CC chemokine receptor 4 monoclonal antibody, mogamulizumab, before allogeneic bone marrow transplantation for adult T-cell leukemia/lymphoma
Administration of an anti-CC chemokine receptor 4 monoclonal antibody, mogamulizumab, before allogeneic bone marrow… 
2008
2008
Serum concentrations of CCR4 ligands in relation to clinical severity of atopic dermatitis in Egyptian children
T helper 2 (Th2) lymphocytes, the key effector cells in pathogenesis of atopic dermatitis (AD), express CCR4 receptors. CCR4… 
2005
2005
Production of a monoclonal antibody to canine thymus and activation-regulated chemokine (TARC) and detection of TARC in lesional skin from dogs with atopic dermatitis.
Review
2005
Review
2005
Chemokine receptors and transplantation.
A complex process including both the innate and acquired immune responses results in allograft rejection. Some chemokine… 
2003
2003
Molecular cloning of the feline thymus and activation-regulated chemokine cDNA and its expression in lesional skin of cats with eosinophilic plaque.
Thymus and activation-regulated chemokine (TARC) is a member of CC chemokine and plays an essential role in recruitment of CC… 
2002
2002
IL-4, but not IL-13, modulates TARC (thymus and activation-regulated chemokine)/CCL17 and IP-10 (interferon-induced protein of 10kDA)/CXCL10 release by TNF-alpha and IFN-gamma in HaCaT cell line.
It is known that both interleukin-4 (IL-4) and IL-13 are produced by Th2-type cells and share similar biological functions with… 
2002
2002
Type1 and type2 memory T cells imbalance shown by expression of intrahepatic chemokine receptors relates to pathogenesis of primary biliary cirrhosis.
2002
2002
Expression of CC chemokine receptor 4 (CCR4) mRNA in canine atopic skin lesion.
Review
2001
Review
2001
Antichemokine immunotherapy for allergic diseases
Chemokines have emerged as critical regulators of leukocyte function and as such represent attractive new targets for the therapy… 
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