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Receptors, CCR4

Known as: CC Chemokine Receptors 4, Antigen, CD194, Antigens, CD194 
CCR receptors with specificity for CHEMOKINE CCL17 and CHEMOKINE CCL22. They are expressed at high levels in T-LYMPHOCYTES; MAST CELLS; DENDRITIC… 
National Institutes of Health

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C-C Chemokine Receptor Type 4, humanCCR4 protein, human
CCR4 geneIn Bloodagonistsantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Administration of an anti-CC chemokine receptor 4 monoclonal antibody, mogamulizumab, before allogeneic bone marrow transplantation for adult T-cell leukemia/lymphoma
Administration of an anti-CC chemokine receptor 4 monoclonal antibody, mogamulizumab, before allogeneic bone marrow… 
2016
2016
Development of Engineered T Cells Expressing a Chimeric CD16-CD3ζ Receptor to Improve the Clinical Efficacy of Mogamulizumab Therapy Against Adult T-Cell Leukemia
Purpose: Mogamulizumab (Mog), a humanized anti-CC chemokine receptor 4 (CCR4) mAb that mediates antibody-dependent cellular… 
2013
2013
Suppressive effects of a novel CC chemokine receptor 4 antagonist on Th2 cell trafficking in ligand- and antigen-induced mouse models.
2009
2009
Breaking the A chain: regulating mRNAs in development through CCR4 deadenylase
Post-transcriptional mechanisms of gene regulation have long been implicated in specifying embryonic pattern in many organisms… 
2008
2008
Th1- and Th2-related chemokine and chemokine receptor expression on the ocular surface in endotoxin-induced uveitis
Purpose To determine whether the ocular surface inflammation in uveitis mimics or counteracts intraocular inflammatory pathways… 
2006
2006
All-trans-retinoic acid suppresses interferon-γ and tumor necrosis factor-α; a possible therapeutic agent for rheumatoid arthritis
Objectives: To study the effects of all-trans-retinoic acid (ATRA), we determined the proliferation and cytokine production by… 
Review
2005
Review
2005
Chemokine receptors and transplantation.
A complex process including both the innate and acquired immune responses results in allograft rejection. Some chemokine… 
2005
2005
Immunological development of preterm infants in early infancy
To evaluate the immunological development of preterm infants, especially in early infancy, we examined the serum cytokine levels… 
2002
2002
IL-4, but not IL-13, modulates TARC (thymus and activation-regulated chemokine)/CCL17 and IP-10 (interferon-induced protein of 10kDA)/CXCL10 release by TNF-alpha and IFN-gamma in HaCaT cell line.
It is known that both interleukin-4 (IL-4) and IL-13 are produced by Th2-type cells and share similar biological functions with… 
2002
2002
Type1 and type2 memory T cells imbalance shown by expression of intrahepatic chemokine receptors relates to pathogenesis of primary biliary cirrhosis.
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