CCR4 gene

Known as: CCR4, CMKBR4, C-C Motif Chemokine Receptor 4 Gene 
This gene is involved in chemokine-dependent G protein-coupled receptor signaling.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Regulatory T cells (Tregs) may impede cancer vaccine efficacy in hematologic malignancies and cancer. CCR4 antagonists, an… (More)
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2009
2009
PURPOSE Dry eye disease (DED) is associated with ocular surface inflammation that is thought to be mediated primarily by CD4 T… (More)
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Highly Cited
2007
Highly Cited
2007
Regulatory CD25(+)CD4(+) T cells (Tregs) play an important role in the control of peripheral tolerance. In this study we… (More)
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Highly Cited
2007
Highly Cited
2007
Inflammatory bowel disease (IBD) is an idiopathic inflammatory disease of the intestine. CD4(+) T lymphocytes play an important… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE Atherosclerosis is a chronic immuno-inflammatory disease involving the recruitment of monocytes and T lymphocytes to… (More)
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Highly Cited
2002
Highly Cited
2002
Chemokines and chemokine receptors play important roles in migration and tissue localization of various lymphocyte subsets. Here… (More)
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Highly Cited
2001
Highly Cited
2001
In vitro polarized human Th2 cells preferentially express the chemokine receptors CCR3, CCR4, and CCR8 and migrate to their… (More)
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Highly Cited
2000
Highly Cited
2000
Chemokines play an important role in establishing the distribution of lymphocyte subpopulations in primary and secondary lymphoid… (More)
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Highly Cited
1999
Highly Cited
1999
Helper T cells are classified into Th1 and Th2 subsets based on their profiles of cytokine production. Th1 cells are involved in… (More)
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Highly Cited
1999
Highly Cited
1999
Directed cell movement is integral to both embryogenesis and hematopoiesis. In the adult, the chemokine family of secreted… (More)
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