Skip to search formSkip to main contentSkip to account menu

C-C Chemokine Receptor Type 4, human

Known as: CD194 Antigen, CCR4, CC Chemokine Receptor 4 
C-C chemokine receptor type 4 (360 aa, ~41 kDa) is encoded by the human CCR4 gene. This protein is involved in leukocyte chemotaxis.
National Institutes of Health

Related topics

Related topics

23 relations

Broader (2)

CC cytokine receptor-4Receptors, CCR4
CCR4 geneCCR4 wt AlleleChemokine Receptor GeneChemotaxis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
RNA decay machines: deadenylation by the Ccr4-not and Pan2-Pan3 complexes.
Highly Cited
2011
Highly Cited
2011
The multifunctional Ccr4-Not complex directly promotes transcription elongation.
The Ccr4-Not complex has been implicated in the control of multiple steps of mRNA metabolism; however, its functions in… 
Highly Cited
2006
Highly Cited
2006
The Majority of Human Peripheral Blood CD4+CD25highFoxp3+ Regulatory T Cells Bear Functional Skin-Homing Receptors1
CD4+CD25+ T regulatory cells (Treg) are thought to be important in the peripheral tolerance. Recent evidence suggests that human… 
Highly Cited
2004
Highly Cited
2004
Recapitulation of B cell differentiation in the central nervous system of patients with multiple sclerosis.
Clonally expanded populations of B cells carrying somatic mutations of Ig variable (V) region genes have been detected in the CNS… 
Highly Cited
2001
Highly Cited
2001
C-C Chemokine Receptor 4 Expression Defines a Major Subset of Circulating Nonintestinal Memory T Cells of Both Th1 and Th2 Potential
CCR4, a chemokine receptor for macrophage-derived chemokine (MDC) and thymus and activation-regulated chemokine (TARC), has been… 
Review
2001
Review
2001
Platelet chemokines and their receptors: what is their relevance to platelet storage and transfusion practice?
. The role of platelets as inflammatory cells is demonstrated by the fact that they can release many growth factors and… 
Highly Cited
2000
Highly Cited
2000
A Key Role for Cc Chemokine Receptor 4 in Lipopolysaccharide-Induced Endotoxic Shock
CC chemokine receptor (CCR)4, a high affinity receptor for the CC chemokines thymus and activation-regulated chemokine (TARC) and… 
Highly Cited
2000
Highly Cited
2000
Inducible Expression of a Th2-Type CC Chemokine Thymus- and Activation-Regulated Chemokine by Human Bronchial Epithelial Cells1
CCR4 is now known to be selectively expressed in Th2 cells. Since the bronchial epithelium is recognized as an important source… 
Highly Cited
2000
Highly Cited
2000
Expression pattern of T-cell-associated chemokine receptors and their chemokines correlates with specific subtypes of T-cell non-Hodgkin lymphoma.
Chemokine receptors mediate the migration of lymphocytes through the binding of soluble ligands, and their expression is… 
Highly Cited
1995
Highly Cited
1995
Molecular Cloning and Functional Expression of a Novel CC Chemokine Receptor cDNA from a Human Basophilic Cell Line (*)
We report the cloning and characterization of a novel basophil CC chemokine receptor, K5-5, from the human immature basophilic… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)