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C-C Chemokine Receptor Type 4, human

Known as: CD194 Antigen, CCR4, CC Chemokine Receptor 4 
C-C chemokine receptor type 4 (360 aa, ~41 kDa) is encoded by the human CCR4 gene. This protein is involved in leukocyte chemotaxis.
National Institutes of Health

Related topics

Related topics

23 relations

Broader (2)

CC cytokine receptor-4Receptors, CCR4
CCR4 geneCCR4 wt AlleleChemokine Receptor GeneChemotaxis

Papers overview

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2013
2013
Uncoupling of mRNA synthesis and degradation impairs adaptation to host temperature in Cryptococcus neoformans
The pathogenic fungus Cryptococcus neoformans must overcome multiple stressors to cause disease in its human host. In this study… 
2011
2011
CCL8 and skin T cells—an allergic attraction
The migration of TH2 cells into allergy-affected tissue is key to maintaining the inflammatory response. CCR8-CCL8, a newly… 
2011
2011
In Vivo Dioxin Favors Interleukin-22 Production by Human CD4+ T Cells in an Aryl Hydrocarbon Receptor (AhR)-Dependent Manner
Background The transcription factor aryl hydrocarbon receptor (AhR) mediates the effects of a group of chemicals known as dioxins… 
2011
2011
Percutaneous application of peptidoglycan from Staphylococcus aureus induces infiltration of CCR4+ cells into mouse skin.
BACKGROUND The lesional skin of patients with atopic dermatitis has an increased number of type 2 helper T (TH2) cells in the… 
Highly Cited
2009
Highly Cited
2009
The CCR4-NOT Complex Physically and Functionally Interacts with TRAMP and the Nuclear Exosome
Background Ccr4-Not is a highly conserved multi-protein complex consisting in yeast of 9 subunits, including Not5 and the major… 
2006
2006
Genetic Interactions Between Nhp6 and Gcn5 With Mot1 and the Ccr4–Not Complex That Regulate Binding of TATA-Binding Protein in Saccharomyces cerevisiae
Our previous work suggests that the Nhp6 HMGB protein stimulates RNA polymerase II transcription via the TATA-binding protein TBP… 
Highly Cited
2005
Highly Cited
2005
CCL22‐induced responses are powerfully enhanced by synergy inducing chemokines via CCR4: evidence for the involvement of first β‐strand of chemokine
In an attempt to clarify how cells integrate the signals provided by multiple chemokines expressed during inflammation, we have… 
2005
2005
Differential expression of chemokine receptors on human IgA+ and IgG+ B cells
Organ‐specific lymphocyte homing is dependent on the expression of tissue‐specific homing receptors and selected chemokine… 
Review
2005
Review
2005
Expression of CCR4 in adult T-cell leukemia
Adult T-cell leukemia (ATL) is a malignancy of mature T cells that is etiologically associated with human T-cell leukemia virus… 
2002
2002
Dominant expression of CXCR3 is associated with induced expression of IP-10 at hapten-challenged sites of murine contact hypersensitivity: a possible role for interferon-gamma-producing CD8(+) T…
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