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Receptors, Serotonin, 5-HT4

Known as: Receptor, 5-HT4, Receptor, 5-Hydroxytryptamine-4, 5-Hydroxytryptamine-4 Receptor 
A subtype of G-protein-coupled SEROTONIN receptors that preferentially couple to GS STIMULATORY G-PROTEINS resulting in increased intracellular… 
National Institutes of Health

Related topics

Related topics

4 relations
HTR4 geneIn Bloodaspects of radiation effectsphysiological aspects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2001
Highly Cited
2001
Tegaserod, a 5‐HT4 receptor partial agonist, accelerates gastric emptying and gastrointestinal transit in healthy male subjects
Serotonin and its type‐4 (5‐hydroxytryptamine4) receptor play a major role in the physiology of the gastrointestinal tract. The… 
Highly Cited
2001
Highly Cited
2001
The Human Serotonin 5-HT4 Receptor Regulates Secretion of Non-amyloidogenic Precursor Protein*
The serotonin 5-HT4receptor has recently gained a lot of attention for its functional roles in central processes such as memory… 
Highly Cited
1997
Highly Cited
1997
Comparison of effect of mosapride citrate and existing 5-HT4 receptor agonists on gastrointestinal motility in vivo and in vitro.
Mosapride citrate is a new gastroprokinetic agent that enhances the upper GI motility by stimulating 5-hydroxytryptamine4 (5-HT4… 
Highly Cited
1996
Highly Cited
1996
Lesion Study of the Distribution of Serotonin 5‐HT4 Receptors in Rat Basal Ganglia and Hippocampus
The regional distribution of 5‐hydroxytryptamine (5‐HT4) receptors labelled with [3H]GR113808 was examined in rat basal ganglia… 
Review
1996
Review
1996
Peripheral 5‐HT4 receptors
The 5‐HT4 receptor is a member of the seven transmembrane spanning G‐protein‐cou‐pled family of receptors. The receptor is… 
Highly Cited
1995
Highly Cited
1995
The 5‐HT4 receptor: molecular cloning and pharmacological characterization of two splice variants.
Molecular cloning efforts have provided primary amino acid sequence and signal transduction data for a large collection of… 
Review
1995
Review
1995
Central 5-HT4 receptors.
Highly Cited
1995
Highly Cited
1995
The serotonin 5-HT4 receptor. 2. Structure-activity studies of the indole carbazimidamide class of agonists.
A number of substituted indole carbazimidamides were prepared and evaluated as 5-HT4 receptor agonists by using the isolated… 
Highly Cited
1994
Highly Cited
1994
5-HT4 receptor stimulation facilitates acetylcholine release in rat frontal cortex.
The effect of the serotonergic 5-HT4 receptor agonists BIMU 1 and BIMU 8 on in vivo acetylcholine (ACh) release in brain… 
Highly Cited
1993
Highly Cited
1993
Development of a radioligand binding assay for 5‐HT4 receptors in guinea‐pig and rat brain
1 The 5‐HT4 receptor antagonist, GR113808, has been radiolabelled to a high specific activity with tritium. 2 Characterization of… 
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