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Improvement in Glucose Metabolism After Bariatric Surgery: Comparison of Laparoscopic Roux-en-Y Gastric Bypass and Laparoscopic Sleeve Gastrectomy: A Prospective Randomized Trial
TLDR
Both procedures markedly improved glucose homeostasis: insulin, GLP-1, and PYY levels increased similarly after either procedure, and the results do not support the idea that the proximal small intestine mediates the improvement in glucoseHomeostasis.
Guidelines on the diagnosis and management of iron deficiency and anemia in inflammatory bowel diseases.
TLDR
Recommendations are made regarding diagnostic measures to screen for iron- and other anemia-related deficiencies regarding the triggers for medical intervention, treatment goals, and appropriate therapies.
A meta-analysis of the effect of glucagon-like peptide-1 (7-36) amide on ad libitum energy intake in humans.
TLDR
The aim was to examine the effect of glucagon-like peptide-1 on subsequent energy intake using a data set composed of subject data from previous studies and from two as yet unpublished studies, and investigate whether the effect on energy intake is dose dependent and differs between lean and overweight subjects.
Fecal Calprotectin Correlates More Closely With the Simple Endoscopic Score for Crohn's Disease (SES-CD) than CRP, Blood Leukocytes, and the CDAI
TLDR
Fecal calprotectin was the only marker that reliably discriminated inactive from mild, moderate, and highly active disease, which underlines its usefulness for activity monitoring.
Effect of peptide YY3-36 on food intake in humans.
TLDR
This study shows that intravenous infusions of PYY3-36 decrease spontaneous food intake; the inhibition is, however, only significant at pharmacologic plasma concentrations.
Glucagon-like peptide 1 induces natriuresis in healthy subjects and in insulin-resistant obese men.
TLDR
Intravenous infusions of GLP-1 enhance sodium excretion, reduce H+ secretion, and reduce glomerular hyperfiltration in obese men, suggesting an action at the proximal renal tubule and a potential renoprotective effect.
European evidence based consensus on the diagnosis and management of Crohn’s disease: definitions and diagnosis
TLDR
This document sets out the current European consensus on the diagnosis and management of CD, reached by the European Crohn’s and Colitis Organisation (ECCO) at a meeting held in Prague on 24 September 2004.
Metabolic and Hormonal Changes After Laparoscopic Roux-en-Y Gastric Bypass and Sleeve Gastrectomy: a Randomized, Prospective Trial
TLDR
Bypassing the foregut is not the only mechanism responsible for improved glucose homeostasis, as body weight and BMI decreased markedly and comparably leading to an identical improvement of abnormal glycemic control (HOMA index) in both groups.
Effect of Laparoscopic Sleeve Gastrectomy vs Laparoscopic Roux-en-Y Gastric Bypass on Weight Loss in Patients With Morbid Obesity: The SM-BOSS Randomized Clinical Trial
TLDR
Among patients with morbid obesity, there was no significant difference in excess BMI loss between Laparoscopic sleeve gastrectomy and laparoscopic Roux-en-Y gastric bypass at 5 years of follow-up after surgery.
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