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Receptor, Serotonin, 5-HT2C

Known as: Receptor, 5 Hydroxytryptamine Type 2C, Receptor, 5-HT2C, 5-HT2C Receptor 
A serotonin receptor subtype found primarily in the CENTRAL NERVOUS SYSTEM and the CHOROID PLEXUS. This receptor subtype is believed to mediate the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1963-2018
0204019632018

Related topics

Related topics

4 relations

Narrower (1)

5-Hydroxytryptamine Receptor 2C, human
In Bloodisolation & purification analysisphysiological aspects

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Receptor, Serotonin, 5-HT2C
physiological aspects
In Blood
5-Hydroxytryptamine Receptor 2C, human
isolation & purification analysis

Papers overview

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Highly Cited
2008
Highly Cited
2008
Serotonin 5-HT2C receptor agonist promotes hypophagia via downstream activation of melanocortin 4 receptors.
The neurotransmitter serotonin (5-hydroxytryptamine) is a well-established modulator of energy balance. Both pharmacological and… (More)
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Highly Cited
2007
Highly Cited
2007
Opposing effects of 5-HT2A and 5-HT2C receptor antagonists in the rat and mouse on premature responding in the five-choice serial reaction time test
Serotonin (5-HT) has been linked to impulsivity with recent data suggesting that different receptor sub-types exert opposing… (More)
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Highly Cited
2002
Highly Cited
2002
Altered Editing of Serotonin 2C Receptor Pre-mRNA in the Prefrontal Cortex of Depressed Suicide Victims
Five adenosines within the coding sequence of the serotonin 2C receptor (5-HT2C) pre-mRNA are converted to inosines by RNA… (More)
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Highly Cited
2001
Highly Cited
2001
RNA Editing of the Human Serotonin 5-HT2C Receptor: Alterations in Suicide and Implications for Serotonergic Pharmacotherapy
RNA encoding the human serotonin 5-HT2C receptor (5-HT2CR) undergoes adenosine-to-inosine RNA editing events at five positions… (More)
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Highly Cited
1999
Highly Cited
1999
Reduced satiating effect of d-fenfluramine in serotonin 5-HT2C receptor mutant mice
  Rationale: d-Fenfluramine stimulates the release of serotonin (5-HT) and is a potent inhibitor of the re-uptake of 5-HT into… (More)
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Highly Cited
1999
Highly Cited
1999
Serotonin 5-HT2C receptor RNA editing alters receptor basal activity: implications for serotonergic signal transduction.
Rat and human serotonin 5-HT2C receptor isoforms were evaluated for agonist-independent activation of inositol phosphate… (More)
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Highly Cited
1998
Highly Cited
1998
Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene
Brain serotonin and leptin signaling contribute substantially to the regulation of feeding and energy expenditure. Here we show… (More)
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Highly Cited
1998
Highly Cited
1998
5-HT2C receptor agonists: pharmacological characteristics and therapeutic potential.
In vitro, (S)-2-(chloro-5-fluoro-indol-1-yl)-1-methylethylamine 1:1 C4H4O4 and (S)-2-(4,4,7-trimethyl-1,4-dihydro-indeno[1, 2-b… (More)
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Highly Cited
1996
Highly Cited
1996
Interactions of selective serotonin reuptake inhibitors with the serotonin 5-HT2C receptor
Interactions of the selective serotonin reuptake inhibitors (SSRIs) citalopram, fluoxetine and its main metabolite norfluoxetine… (More)
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Highly Cited
1994
Highly Cited
1994
Distribution of the serotonin 5-HT2 receptor family mRNAs: comparison between 5-HT2A and 5-HT2C receptors.
Because of their similarities, serotonin 5-HT2, 5-HT1C, and the recently described 5-HT2F receptors have been classified as… (More)
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