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RYK gene

Known as: RYK Receptor-Like Tyrosine Kinase Gene, RYK, RYK RECEPTOR-LIKE TYROSINE KINASE 
This gene plays a role in signal transduction.
National Institutes of Health

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Related topics

7 relations
Ligand BindingPhosphorylationProtein Tyrosine KinaseRYK protein, human

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RYK wt Allele

Papers overview

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Highly Cited
2013
Highly Cited
2013
Noncanonical WNT‐5A signaling regulates TGF‐β‐induced extracellular matrix production by airway smooth muscle cells
Transforming growth factor β (TGF‐β), a key mediator of fibrotic responses, is increased in asthma and drives airway remodeling… 
Highly Cited
2012
Highly Cited
2012
The Wnt Receptor Ryk Plays a Role in Mammalian Planar Cell Polarity Signaling*
Background: Ryk acts as a Wnt receptor in several processes, including mouse neuronal development. Results: Ryk interacts with… 
Highly Cited
2008
Highly Cited
2008
Src family kinases are required for WNT5 signaling through the Derailed/RYK receptor in the Drosophila embryonic central nervous system
Members of the RYK/Derailed family have recently been shown to regulate axon guidance in both Drosophila and mammals by acting as… 
Highly Cited
2008
Highly Cited
2008
Ryk cooperates with Frizzled 7 to promote Wnt11-mediated endocytosis and is essential for Xenopus laevis convergent extension movements
The single-pass transmembrane protein Ryk (atypical receptor related tyrosine kinase) functions as a Wnt receptor. However, Ryk's… 
Highly Cited
2004
Highly Cited
2004
Mammalian Ryk Is a Wnt Coreceptor Required for Stimulation of Neurite Outgrowth
Highly Cited
2004
Highly Cited
2004
C. elegans LIN-18 Is a Ryk Ortholog and Functions in Parallel to LIN-17/Frizzled in Wnt Signaling
Highly Cited
1994
Highly Cited
1994
The proto-oncogene of v-eyk (v-ryk) is a novel receptor-type protein tyrosine kinase with extracellular Ig/GN-III domains.
Highly Cited
1993
Highly Cited
1993
NEP: a novel receptor-like tyrosine kinase expressed in proliferating neuroepithelia.
We have isolated a murine cDNA, nep, which encodes a novel receptor-like protein tyrosine kinase. The kinase region of NEP… 
Highly Cited
1992
Highly Cited
1992
RYK, a receptor tyrosine kinase-related molecule with unusual kinase domain motifs.
By using the polymerase chain reaction with degenerate oligonucleotides based on highly conserved motifs held in common between… 
Highly Cited
1990
Highly Cited
1990
The normal erbB-2 product is an atypical receptor-like tyrosine kinase with constitutive activity in the absence of ligand.
Overexpression of the erbB-2/neu gene is frequently detected in human cancers. When overexpressed in NIH 3T3 cells, the normal… 
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