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RRM1 gene

Known as: Ribonucleotide Reductase M1 Gene, RIBONUCLEOTIDE REDUCTASE, LARGE SUBUNIT, RIBONUCLEOTIDE REDUCTASE, M1 SUBUNIT 
This gene plays a role in the inhibition of cell migration, invasion, and metastasis.
National Institutes of Health

Related topics

Related topics

6 relations
Cell ProliferationDNA ReplicationImmunologic Deficiency SyndromesNucleotide Metabolism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
A randomized phase II trial of ERCC1 and RRM1 mRNA expression-based chemotherapy versus docetaxel/carboplatin in advanced non-small cell lung cancer
Objectives To evaluate whether the selection of first-line chemotherapy based on ERCC1 and RRM1 mRNA expression levels would… 
2015
2015
EGFR and K-RAS mutations and ERCC1, TUBB3, TYMS, RRM1 and EGFR mRNA expression in non-small cell lung cancer: Correlation with clinical response to gefitinib or chemotherapy.
Personalizing medicines has refined the traditional treatments for non-small-cell lung cancer (NSCLC). In the present study… 
2015
2015
A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development
ABSTRACT The ribonucleotide reductase (RNR) complex, composed of a catalytic subunit (RRM1) and a regulatory subunit (RRM2), is… 
2014
2014
Prognostic significance of BRCA1, ERCC1, RRM1, and RRM2 in patients with advanced non-small cell lung cancer receiving chemotherapy
The aim of this study was to examine the prognostic value of breast cancer susceptibility gene 1 (BRCA1), excision repair cross… 
2014
2014
Predictive role of RRM1 and BRCA1 mRNA expression on the clinical outcome of advanced non-small cell lung cancer.
This study aimed to evaluate the association between RRM1 and BRCA1 expressions and the therapeutic efficacy of platinum-based… 
2013
2013
Messenger RNA and protein expression of thymidylate synthase and DNA repair genes in thymic tumors.
2012
2012
Gemcitabine metabolic pathway genetic polymorphisms and response in patients with non-small cell lung cancer
Background and objective Gemcitabine is widely used to treat non-small cell lung cancer (NSCLC). The aim of this study was to… 
2012
2012
[Expression of RRM1 and ERCC1 genes in tumor tissues and peripheral blood lymphocytes of advanced non-small cell lung cancer].
OBJECTIVE To investigate the expression of RRM1 and ERCC1 genes in tumor tissues and peripheral blood lymphocytes of advanced non… 
2010
2010
Histology- and gender-related associations of ERCC1, RRM1, and TS biomarkers in 1,802 patients with NSCLC: Implications for therapy.
7513 Background: Histology-based decision making for non-small cell lung cancer (NSCLC) has recently been advocated. We… 
1992
1992
The M1 subunit of ribonucleotide reductase refines mapping of genetic rearrangements at chromosome 11p15.
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