RRM1 gene

Known as: Ribonucleotide Reductase M1 Gene, RIBONUCLEOTIDE REDUCTASE, LARGE SUBUNIT, RIBONUCLEOTIDE REDUCTASE, M1 SUBUNIT 
This gene plays a role in the inhibition of cell migration, invasion, and metastasis.

Topic mentions per year

Topic mentions per year

1990-2017
0102019902017

Papers overview

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2011
2011
The excision repair cross completing group 1 gene product (ERCC1) and the regulatory subunit of ribonucleotide reductase (RRM1… (More)
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2009
2009
The identification of molecular markers, useful for therapeutic decisions in pancreatic cancer patients, is crucial for advances… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE We evaluated the efficacy of gemcitabine versus gemcitabine and carboplatin in patients with advanced non-small-cell lung… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Overexpression of RRM1 and RRM2 has been associated with gemcitabine resistance. BRCA1 overexpression increases… (More)
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2008
2008
BACKGROUND Endobronchial forceps biopsies are often small and are associated with a relevant extent of artifacts. To overcome… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND RRM1, the regulatory subunit of ribonucleotide reductase, is involved in carcinogenesis, tumor progression, and the… (More)
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2007
2007
PURPOSE We examined the pattern of single-nucleotide polymorphisms (SNPs) of gemcitabine metabolism-related and target genes in… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Pivotal studies indicate a role of excision repair cross-complementation 1 (ERCC1) gene and ribonucleotide reductase… (More)
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Highly Cited
2004
Highly Cited
2004
PURPOSE RRM1 has important functions in the determination of the malignant phenotype. It controls cell proliferation through… (More)
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1999
1999
LOH11A is a region of Chromosome (Chr) 11p15.5 where 75% of lung cancers show loss of heterozygosity (LOH). Clinical and cell… (More)
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