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RNASEN wt Allele

Known as: HSA242976, Etohi2, RN3 
Human RNASEN wild-type allele is located in the vicinity of 5p13.3 and is approximately 131 kb in length. This allele, which encodes ribonuclease III… 
National Institutes of Health

Related topics

Related topics

6 relations
5p13.3DROSHA geneHydrolysisRNA Degradation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Cytoplasmic Drosha activity generated by alternative splicing
RNase III enzyme Drosha interacts with DGCR8 to form the Microprocessor, initiating canonical microRNA (miRNA) maturation in the… 
Highly Cited
2014
Highly Cited
2014
Drosha as an interferon-independent antiviral factor
Significance Virus infections must be combated at a cellular level. The strategies used to inhibit virus differ dramatically when… 
2014
2014
The expression of Dicer and Drosha in matched normal tissues, tumours and lymph node metastases in triple negative breast cancer
BackgroundBreast cancer is the most common malignancy in women world-wide. Triple negative breast cancer (TNBC) is a highly… 
2013
2013
MicroRNA-related genetic variants associated with clinical outcomes in early-stage non-small cell lung cancer patients.
Given the density of single-nucleotide polymorphisms (SNP) in the human genome and the sensitivity of single-nucleotide changes… 
2013
2013
Genetic Variation in DROSHA 3’UTR Regulated by hsa-miR-27b Is Associated with Bladder Cancer Risk
Purpose miRNAs can regulate the biological processes, including differentiation, proliferation and apoptosis. DICER and DROSHA… 
Highly Cited
2012
Highly Cited
2012
Downregulated Dicer expression predicts poor prognosis in chronic lymphocytic leukemia
Chronic lymphocytic leukemia (CLL) is the most common leukemia in the western world. Alterations in microRNAs (miRNAs) expression… 
2011
2011
Upregulation of Dicer is more frequent in monoclonal gammopathies of undetermined significance than in multiple myeloma patients and is associated with longer survival in symptomatic myeloma patients
Dicer and Drosha are key enzymes in the miRNA-processing pathway which is altered in many human cancers. We analyzed Dicer and… 
Review
2011
Review
2011
Can Lymph Node Ratio Take the Place of pN Categories in the UICC/AJCC TNM Classification System for Colorectal Cancer?
BackgroundLymph node ratio (LNR) has been reported to represent a powerful independent prognostic value in some malignancies. The… 
2010
2010
Short interfering RNA-mediated knockdown of drosha and pasha in undifferentiated Meloidogyne incognita eggs leads to irregular growth and embryonic lethality.
2000
2000
Novel mutual prodrug of retinoic and butyric acids with enhanced anticancer activity.
Acyloxylalkyl esters of retinoic acid and small carboxylic acids (C3-5) were evaluated for anticancer activity. The derivative of… 
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