DROSHA gene

Known as: drosha ribonuclease III, drosha, ribonuclease type III, RIBONUCLEASE III, NUCLEAR 
This gene plays a role in the processing of microRNA in the nucleus.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The Drosha-DGCR8 complex, also known as Microprocessor, is essential for microRNA (miRNA) maturation. Drosha functions as the… (More)
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Highly Cited
2008
Highly Cited
2008
MicroRNAs (miRNAs) are small non-coding RNAs that participate in the spatiotemporal regulation of messenger RNA and protein… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND We studied Dicer and Drosha, components of the RNA-interference machinery, in ovarian cancer. METHODS We measured… (More)
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Highly Cited
2008
Highly Cited
2008
MicroRNAs (miRNAs) are implicated in the differentiation and function of many cell types. We provide genetic and in vivo evidence… (More)
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Highly Cited
2007
Highly Cited
2007
MicroRNAs (miRNAs) are ∼22-nucleotide endogenous RNAs that often repress the expression of complementary messenger RNAs. In… (More)
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Highly Cited
2007
Highly Cited
2007
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression by binding to the cellular transcript leading to… (More)
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Highly Cited
2006
Highly Cited
2006
The Drosha-DGCR8 complex initiates microRNA maturation by precise cleavage of the stem loops that are embedded in primary… (More)
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Highly Cited
2005
Highly Cited
2005
A critical step during human microRNA maturation is the processing of the primary microRNA transcript by the nuclear RNaseIII… (More)
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Highly Cited
2004
Highly Cited
2004
RNase III proteins play key roles in microRNA (miRNA) biogenesis. The nuclear RNase III Drosha cleaves primary miRNAs (pri-miRNAs… (More)
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Highly Cited
2003
Highly Cited
2003
Hundreds of small RNAs of ∼22 nucleotides, collectively named microRNAs (miRNAs), have been discovered recently in animals and… (More)
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