REST wt Allele

Known as: NRSF, RE1-Silencing Transcription Factor wt Allele, XBR 
Human REST wild-type allele is located in the vicinity of 4q12 and is approximately 28 kb in length. This allele, which encodes RE1-silencing… (More)
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
We developed the Genomic Regions Enrichment of Annotations Tool (GREAT) to analyze the functional significance of cis-regulatory… (More)
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Highly Cited
2008
Highly Cited
2008
Molecular interactions between protein complexes and DNA mediate essential gene-regulatory functions. Uncovering such… (More)
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Highly Cited
2006
Highly Cited
2006
Temporal lobe epilepsy is a common form of drug-resistant epilepsy that sometimes responds to dietary manipulation such as the… (More)
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Highly Cited
2006
Highly Cited
2006
Two distinct classes of regulators have been implicated in regulating neuronal gene expression and mediating neuronal identity… (More)
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Highly Cited
2003
Highly Cited
2003
Huntingtin protein is mutated in Huntington disease. We previously reported that wild-type but not mutant huntingtin stimulates… (More)
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Highly Cited
1999
Highly Cited
1999
Several genes encoding proteins critical to the neuronal phenotype, such as the brain type II sodium channel gene, are expressed… (More)
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Highly Cited
1999
Highly Cited
1999
Many genes whose expression is restricted to neurons in the brain contain a silencer element (RE1/NRSE) that limits transcription… (More)
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Highly Cited
1998
Highly Cited
1998
The neuron-restrictive silencer factor NRSF (also known as REST and XBR) can silence transcription from neuronal promoters in non… (More)
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Highly Cited
1998
Highly Cited
1998
The identification of a common cis-acting silencer element, a neuron-restrictive silencer element (NRSE), in multiple neuron… (More)
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Highly Cited
1996
Highly Cited
1996
The neuron-restrictive silencer factor (NRSF) represses transcription of several neuronal genes in nonneuronal cells by binding… (More)
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