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RAF1 gene

Known as: TRANSFORMING REPLICATION-DEFECTIVE MURINE RETROVIRUS 3611-MSV, V-RAF-1 MURINE LEUKEMIA VIRAL ONCOGENE HOMOLOG 1, C-Raf proto-oncogene, serine/threonine kinase 
This gene is involved in cell growth, proliferation, differentiation and migration. It also plays a role in apoptosis.
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Raf-1 protects cells from apoptosis, independently of its signals to MEK and ERK, by translocating to the mitochondria where it… 
Highly Cited
2002
Highly Cited
2002
The Raf kinases are key signal transducers activated by mitogens or oncogenes. The best studied Raf isoform, Raf-1, was… 
Highly Cited
2001
Highly Cited
2001
ABSTRACT The Raf-1 serine/threonine protein kinase requires phosphorylation of the serine at position 338 (S338) for activation… 
Highly Cited
1999
Highly Cited
1999
The gene encoding the cyclin-dependent kinase inhibitor p21Cip1/Waf1 is up-regulated in many differentiating cells, including… 
Highly Cited
1997
Highly Cited
1997
Activation of early response genes by interferons (IFNs) and other cytokines requires tyrosine phosphorylation of a family of… 
Highly Cited
1993
Highly Cited
1993
Ras is involved in signal transduction of various factors for growth, differentiation, and oncogenesis. Recent studies have… 
Highly Cited
1993
Highly Cited
1993
Mitogen-activated protein (MAP) kinases Raf-1, pp60src, and p21ras all play important roles in the transfer of signals from the… 
Highly Cited
1991
Highly Cited
1991
The product of the c-raf-1 proto-oncogene, Raf-1, is a 74,000-dalton cytoplasmic serine/threonine protein kinase that has been… 
Highly Cited
1991
Highly Cited
1991
To gain further insight into the role of Raf-1 in normal cell growth, c-raf-1 mRNA expression, Raf-1 protein production, and Raf…