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RAF1 gene

Known as: TRANSFORMING REPLICATION-DEFECTIVE MURINE RETROVIRUS 3611-MSV, V-RAF-1 MURINE LEUKEMIA VIRAL ONCOGENE HOMOLOG 1, C-Raf proto-oncogene, serine/threonine kinase 
This gene is involved in cell growth, proliferation, differentiation and migration. It also plays a role in apoptosis.
National Institutes of Health

Related topics

Related topics

14 relations
Cell Cycle ControlMAP Kinase Kinase Kinase 1MAP kinase kinase activityMAP3K1 gene

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RAF1 wt Allele

Papers overview

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2019
2019
Biased TAS2R Bronchodilators Inhibit Airway Smooth Muscle Growth by Downregulating pERK1/2
Bitter taste receptor (TAS2R) agonists dilate airways by receptor-dependent smooth muscle relaxation. Besides coupling to… 
2015
2015
Effectively targeting CRAF: rational serendipity targeting SRC?
In the January 12th issue of Cancer Cell (27, 2015: 1–12), Girotti and colleagues report further progress toward the goal of… 
2014
2014
Study of the role of RAF-1 in MAPK signaling in thyroid cancer cells
Thyroid cancer is the most common endocrine malignancy, accounting to 94% of endocrine system cancers and 66% of deaths due to… 
2012
2012
Abstract LB-14: Raf-1 in epithelial-mesenchymal transition: a novel therapeutic target for ovarian and endometrial cancers
Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL Ovarian and endometrial cancers are the 5th and… 
2009
2009
Toll-like Receptor 2 and DC-SIGNR 1 Differentially Regulate Suppressors of Cytokine Signaling 1 in Dendritic Cells during Mycobacterium tuberculosis Infection *
Varsha Srivastava, Mini Manchanda, Shashank Gupta, Rupak Singla, Digamber Behera, Gobardhan Das, and Krishnamurthy Natarajan From… 
2006
2006
Activation in NIH 3 T 3 Cells Like ( RGL ) Reverses v-Ras-induced Transformation and Raf-1 Ras-interacting Domain of Ral GDP Dissociation Stimulator
Ral GDP dissociation stimulator (RalGDS) and RalGDS like (RGL) are putative effector proteins of Ras and contain the Ras… 
2005
2005
The cytokine-activated tyrosine kinase JAK 2 activates Raf-1 in a p 21 ras-dependent manner ( signal transduction / baculovirus / mammalian cells / oncogenes )
JAK2, a member of the Janus kinase superfamily was found to interact functionally with Raf-1, a central component of the ras… 
2002
2002
A Randomized Phase II and Pharmacokinetic Study of the Antisense Oligonucleotides ISIS 3521 and ISIS 5132 in Patients with Hormone-refractory Prostate Cancer 1
Purpose: Protein kinase C (PKC)and Raf-1 are important elements of proliferative signal transduction pathways in both normal and… 
Review
1998
Review
1998
Autoregulation of the Raf-1 serine y threonine kinase ( signal transduction
The Raf-1 serineythreonine kinase is a key protein involved in the transmission of many growth and developmental signals. In this… 
1985
1985
Genetic analysis of alphafetoprotein levels in BALB/c sublines.
Alphafetoprotein (AFP) is the major serum protein of fetal animals. It is closely related to albumin in structure (Ruoslahti and…