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MAP Kinase Kinase Kinase 1

Known as: MAP3K1 Protein, MEK Kinase 1, MAP Kinase Kinase Kinase 1 [Chemical/Ingredient] 
A 195-kDa zinc finger motif-containing MAP kinase kinase kinase with broad specificity for MAP KINASE KINASES. It localizes to the CYTOSKELETON and… 
National Institutes of Health

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In BloodMAP Kinase Kinase 1MAP kinase kinase kinase activityMAP3K1 gene

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MAP3K1 protein, human

Papers overview

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2011
2011
MEK kinase 1: kinase domain deficiency in mice reveals a role in orchestrating the thymus-dependent immunity and TNFR family signaling.
Almost 20 years ago early work led to the cloning and identification of mitogen-activated protein kinases (MAPKs) as the apical… 
2007
2007
Molecular Mechanism of Tenascin-C Action on Matrix Metalloproteinase-1 Invasive Potential
The aim of the current study was to confirm that tenascin-C large splice variant (TNC320) stimulates matrix metalloproteinase-1… 
2001
2001
5-Fluorouracil suppression of NF-KappaB is mediated by the inhibition of IKappab kinase activity in human salivary gland cancer cells.
We have recently shown that 5-Fluorouracil (5-FU) suppresses the transcription factor NF-kappaB in human salivary gland cancer… 
2001
2001
c-Jun NH2-terminal kinase-mediated redox-dependent degradation of IkappaB: role of thioredoxin in NF-kappaB activation.
NF-kappaB is a redox-sensitive transcription factor known to be activated by oxidative stress as well as chemical and biological… 
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