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MAP Kinase Kinase Kinase 1
Known as:
MAP3K1 Protein
, MEK Kinase 1
, MAP Kinase Kinase Kinase 1 [Chemical/Ingredient]
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A 195-kDa zinc finger motif-containing MAP kinase kinase kinase with broad specificity for MAP KINASE KINASES. It localizes to the CYTOSKELETON and…
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National Institutes of Health
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Related topics
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14 relations
In Blood
MAP Kinase Kinase 1
MAP kinase kinase kinase activity
MAP3K1 gene
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Narrower (1)
MAP3K1 protein, human
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Mutation analysis of mitogen activated protein kinase 1 gene in Indian cases of 46,XY disorder of sex development
D. Das
,
Subodh G Rahate
,
Bhakti P Mehta
,
H. Gawde
,
P. Tamhankar
Indian journal of human genetics
2013
Corpus ID: 207464555
BACKGROUND: Determination of sex is the result of cascade of molecular events that cause undifferentiated bipotential gonad to…
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2011
2011
MEK kinase 1: kinase domain deficiency in mice reveals a role in orchestrating the thymus-dependent immunity and TNFR family signaling.
E. Gallagher
Advances in experimental medicine and biology
2011
Corpus ID: 21370651
Almost 20 years ago early work led to the cloning and identification of mitogen-activated protein kinases (MAPKs) as the apical…
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Highly Cited
2009
Highly Cited
2009
Hormone-dependent effects of FGFR2 and MAP3K1 in breast cancer susceptibility in a population-based sample of post-menopausal African-American and European-American women.
T. Rebbeck
,
A. DeMichele
,
+4 authors
B. Strom
Carcinogenesis
2009
Corpus ID: 8018989
FGFR2 and MAP3K1 are members of the RAS/RAF/MEK/ERK-signaling pathway and have been identified from genome-wide association…
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2005
2005
D-MEKK1, the Drosophila orthologue of mammalian MEKK4/MTK1, and Hemipterous/D-MKK7 mediate the activation of D-JNK by cadmium and arsenite in Schneider cells
O. Ryabinina
,
Ezhilkani Subbian
,
M. Iordanov
BMC Cell Biology
2005
Corpus ID: 16949659
BackgroundThe family of c-Jun NH2-terminal kinases (JNK) plays important roles in embryonic development and in cellular responses…
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2002
2002
Scaffold Role of a Mitogen-activated Protein Kinase Phosphatase, SKRP1, for the JNK Signaling Pathway*
T. Zama
,
Ryoko Aoki
,
T. Kamimoto
,
Koichi Inoue
,
Yasuo Ikeda
,
M. Hagiwara
The Journal of Biological Chemistry
2002
Corpus ID: 12430487
Stress-activated protein kinase (SAPK) pathway-regulating phosphatase 1 (SKRP1) has been identified as a member of the mitogen…
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Highly Cited
2001
Highly Cited
2001
The NF-kappaB pathway in human endometrium and first trimester decidua.
A. E. King
,
H. Critchley
,
R. Kelly
Molecular human reproduction
2001
Corpus ID: 44662480
Nuclear factor kappa B (NF-kappaB) regulates proinflammatory genes and may be involved in inflammation associated with…
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Highly Cited
1998
Highly Cited
1998
Regulation of Apoptosis by α-Subunits of G12 and G13 Proteins via Apoptosis Signal-regulating Kinase-1*
Y. Berestetskaya
,
M. Faure
,
H. Ichijo
,
T. Voyno-Yasenetskaya
The Journal of Biological Chemistry
1998
Corpus ID: 23405631
Many growth factors and G protein-coupled receptors activate mitogen-activated protein (MAP) kinase pathways. The MAP kinase…
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Highly Cited
1998
Highly Cited
1998
Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase.
S. Nemoto
,
J. DiDonato
,
A. Lin
Molecular and cellular biology
1998
Corpus ID: 12288275
IkappaB kinases (IKKalpha and IKKbeta) are key components of the IKK complex that mediates activation of the transcription factor…
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Highly Cited
1997
Highly Cited
1997
Regulation of the activity of MEK kinase 1 (MEKK1) by autophosphorylation within the kinase activation domain.
J. Deak
,
D. Templeton
The Biochemical journal
1997
Corpus ID: 39647824
MEK kinase 1 (MEKK1) shares sequence identity with the yeast kinases Ste11 and Byr2, and is capable of phosphorylation and…
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Highly Cited
1996
Highly Cited
1996
Interaction between c-Rel and the Mitogen-activated Protein Kinase Kinase Kinase 1 Signaling Cascade in Mediating B Enhancer Activation (*)
C. Meyer
,
X. Wang
,
C. Chang
,
D. Templeton
,
T. Tan
The Journal of Biological Chemistry
1996
Corpus ID: 24336273
The Rel family of transcription factors are important mediators of various cytokine stimuli such as interleukin (IL)-1, tumor…
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