RAF1 wt Allele

Known as: cRAF, v-RAF-1 Murine Leukemia Viral Oncogene Homolog 1wt Allele, Raf-1 
Human RAF1 wild-type allele is located within 3p25 and is approximately 81 kb in length. This allele, which encodes RAF proto-oncogene serine… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The C-type lectin dectin-1 activates the transcription factor NF-κB through a Syk kinase–dependent signaling pathway to induce… (More)
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Review
2006
Review
2006
Miltefosine (hexadecylphosphocholine, MIL), registered as Impavido((R)), has become the first oral drug for the treatment of… (More)
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Highly Cited
2001
Highly Cited
2001
Survival after stress requires the precise orchestration of cell-signalling events to ensure that biosynthetic processes are… (More)
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Highly Cited
2000
Highly Cited
2000
Enrichment of Neuro 2A cells with docosahexaenoic acid (22:6n-3) decreased apoptotic cell death induced by serum starvation as… (More)
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Highly Cited
1999
Highly Cited
1999
The primary known function of phospholipase D (PLD) is to generate phosphatidic acid (PA) via the hydrolysis of… (More)
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Highly Cited
1998
Highly Cited
1998
The pathway involving the signalling protein p21Ras propagates a range of extracellular signals from receptors on the cell… (More)
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Highly Cited
1996
Highly Cited
1996
c-Raf-1 (Raf-1) is a central component of signal transduction pathways stimulated by various growth factors, protein kinase C… (More)
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Highly Cited
1996
Highly Cited
1996
The serine/threonine kinase Raf-1 functions downstream of Rats in a signal transduction cascade which transmits mitogenic stimuli… (More)
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Highly Cited
1994
Highly Cited
1994
THE protein Raf-1, a key mediator of mitogenesis and differentia-tion, associates with p21*"a5 (refs 1-3). However, the… (More)
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Highly Cited
1992
Highly Cited
1992
Raf-1 serine-threonine protein kinase has the hallmarks of a critical switch that connects growth factor receptor activation at… (More)
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