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RAD21 gene

Known as: RAD21, S. POMBE, HOMOLOG OF, HR21, NXP1 
This gene is involved in chromosomal cohesion, DNA repair and apoptosis.
National Institutes of Health

Related topics

Related topics

9 relations
ApoptosisChromosome CondensationDNA RepairDouble Strand Break Repair

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RAD21 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
The regulatory and predictive functions of miR-17 and miR-92 families on cisplatin resistance of non-small cell lung cancer
BackgroundChemotherapy is an important therapeutic approach for non-small cell lung cancer (NSCLC). However, a successful long… 
Highly Cited
2010
Highly Cited
2010
Missense polymorphisms of PTPRJ and PTPN13 genes affect susceptibility to a variety of human cancers
PurposeWe investigated the association between incidence of various cancers and four single nucleotide polymorphisms (SNPs), two… 
2010
2010
Rad21 is required for centrosome integrity in human cells independently of its role in chromosome cohesion.
Classically, chromosomal functions in DNA repair and sister chromatid association have been assigned to the cohesin proteins… 
2008
2008
Phosphorylation-dependent Binding of Cyclin B1 to a Cdc6-like Domain of Human Separase*
Sister chromatids are held together by the ring-shaped cohesin complex, which likely entraps both DNA-double strands in its… 
Highly Cited
2007
Highly Cited
2007
A mutation in a chromosome condensin II subunit, kleisin β, specifically disrupts T cell development
Condensins are ubiquitously expressed multiprotein complexes that are important for chromosome condensation and epigenetic… 
Highly Cited
2004
Highly Cited
2004
Preferential cleavage of chromatin‐bound cohesin after targeted phosphorylation by Polo‐like kinase
The final irreversible step in the duplication and dissemination of eukaryotic genomes takes place when sister chromatid pairs… 
Review
2004
Review
2004
From a single double helix to paired double helices and back.
The propagation of our genomes during cell proliferation depends on the movement of sister DNA molecules produced by DNA… 
Highly Cited
2002
Highly Cited
2002
Linking Sister Chromatid Cohesion and Apoptosis: Role of Rad21
ABSTRACT Rad21 is one of the major cohesin subunits that holds sister chromatids together until anaphase, when proteolytic… 
Highly Cited
1995
Highly Cited
1995
The rad21 Gene Product of Schizosaccharomyces pombe Is a Nuclear, Cell Cycle-regulated Phosphoprotein (*)
The rad21 gene of Schizosaccharomyces pombe is involved in the repair of double-strand breaks in DNA and is essential for mitotic… 
1977
1977
Alkaline sucrose sedimentation studies of MMS-induced DNA single-strand breakage and rejoining in the wild type and in UV-sensitive mutants of Saccharomyces cerevisiae.
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