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RAD21 gene

Known as: RAD21, S. POMBE, HOMOLOG OF, HR21, NXP1 
This gene is involved in chromosomal cohesion, DNA repair and apoptosis.
National Institutes of Health

Related topics

Related topics

9 relations
ApoptosisChromosome CondensationDNA RepairDouble Strand Break Repair

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RAD21 wt Allele

Papers overview

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Highly Cited
2010
Highly Cited
2010
Rec8-containing cohesin maintains bivalents without turnover during the growing phase of mouse oocytes.
During female meiosis, bivalent chromosomes are thought to be held together from birth until ovulation by sister chromatid… 
Highly Cited
2008
Highly Cited
2008
The kleisin subunit of cohesin dictates damage-induced cohesion.
Highly Cited
2005
Highly Cited
2005
Dissociation of Cohesin from Chromosome Arms and Loss of Arm Cohesion during Early Mitosis Depends on Phosphorylation of SA2
Cohesin is a protein complex that is required to hold sister chromatids together. Cleavage of the Scc1 subunit of cohesin by the… 
Highly Cited
2005
Highly Cited
2005
Shugoshin Prevents Dissociation of Cohesin from Centromeres During Mitosis in Vertebrate Cells
Cohesion between sister chromatids is essential for their bi-orientation on mitotic spindles. It is mediated by a multisubunit… 
Highly Cited
2005
Highly Cited
2005
Suppression of RAD21 gene expression decreases cell growth and enhances cytotoxicity of etoposide and bleomycin in human breast cancer cells
A genome-wide case-control association study done in our laboratory has identified a single nucleotide polymorphism located in… 
Highly Cited
2003
Highly Cited
2003
Kleisins: a superfamily of bacterial and eukaryotic SMC protein partners.
Highly Cited
2003
Highly Cited
2003
ATP Hydrolysis Is Required for Cohesin's Association with Chromosomes
Highly Cited
2000
Highly Cited
2000
Pds5 cooperates with cohesin in maintaining sister chromatid cohesion
Highly Cited
2000
Highly Cited
2000
Characterization of fission yeast cohesin: essential anaphase proteolysis of Rad21 phosphorylated in the S phase.
Cohesin complex acts in the formation and maintenance of sister chromatid cohesion during and after S phase. Budding yeast Scc1p… 
Highly Cited
1992
Highly Cited
1992
Cloning and characterization of rad21 an essential gene of Schizosaccharomyces pombe involved in DNA double-strand-break repair.
Analysis of the Schizosaccharomyces pombe chromosomes by pulsed field gel electrophoresis showed that the fission yeast has a… 
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