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RABEP1 protein, human

Known as: neurocrescin protein, human, RAB5EP protein, human, neurocrescin, NOGF protein, human 
Rab GTPase-binding effector protein 1 (862 aa, ~99 kDa) is encoded by the human RABEP1 gene. This protein is involved in both the mediation of… 
National Institutes of Health

Related topics

Related topics

8 relations
CytoplasmEarly endosomeEndocytosisRABEP1 gene

Broader (1)

Vesicular Transport Proteins

Papers overview

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Highly Cited
2003
Highly Cited
2003
Divalent interaction of the GGAs with the Rabaptin‐5–Rabex‐5 complex
Cargo transfer from trans‐Golgi network (TGN)‐derived transport carriers to endosomes involves a still undefined set of tethering… 
Highly Cited
2001
Highly Cited
2001
Functional synergy between Rab5 effector Rabaptin-5 and exchange factor Rabex-5 when physically associated in a complex.
Rab GTPases are central elements of the vesicular transport machinery. An emerging view is that downstream effectors of these… 
Highly Cited
2001
Highly Cited
2001
Rabaptin-5 is a novel fusion partner to platelet-derived growth factor beta receptor in chronic myelomonocytic leukemia.
Chromosomal translocations involving the platelet-derived growth factor beta receptor (PDGFbetaR) gene have been reported in some… 
Highly Cited
2000
Highly Cited
2000
Selective Membrane Recruitment of EEA1 Suggests a Role in Directional Transport of Clathrin-coated Vesicles to Early Endosomes*
The molecular mechanisms ensuring directionality of endocytic membrane trafficking between transport vesicles and target… 
Highly Cited
1998
Highly Cited
1998
Distinct Rab‐binding domains mediate the interaction of Rabaptin‐5 with GTP‐bound rab4 and rab5
Rabaptin‐5 functions as an effector for the small GTPase Rab5, a regulator of endocytosis and early endosome fusion. We have… 
Highly Cited
1998
Highly Cited
1998
Two distinct effectors of the small GTPase Rab5 cooperate in endocytic membrane fusion
Using the yeast two‐hybrid system, we have identified a novel 62 kDa coiled‐coil protein that specifically interacts with the GTP… 
Highly Cited
1998
Highly Cited
1998
The Neuronal Growth-Associated Protein GAP-43 Interacts with Rabaptin-5 and Participates in Endocytosis
Structural plasticity of nerve cells is a requirement for activity-dependent changes in the brain. The growth-associated protein… 
Highly Cited
1997
Highly Cited
1997
A Novel Rab5 GDP/GTP Exchange Factor Complexed to Rabaptin-5 Links Nucleotide Exchange to Effector Recruitment and Function
Highly Cited
1997
Highly Cited
1997
The Tuberous Sclerosis 2 Gene Product, Tuberin, Functions as a Rab5 GTPase Activating Protein (GAP) in Modulating Endocytosis*
The tuberous sclerosis complex 2 (TSC2) is a tumor suppressor gene that plays a causative role in the autosomal dominant syndrome… 
Highly Cited
1995
Highly Cited
1995
Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion
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