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RABEP1 protein, human

Known as: neurocrescin protein, human, RAB5EP protein, human, neurocrescin, NOGF protein, human 
Rab GTPase-binding effector protein 1 (862 aa, ~99 kDa) is encoded by the human RABEP1 gene. This protein is involved in both the mediation of… 
National Institutes of Health

Related topics

Related topics

8 relations
CytoplasmEarly endosomeEndocytosisRABEP1 gene

Broader (1)

Vesicular Transport Proteins

Papers overview

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Highly Cited
2012
Highly Cited
2012
VipD of Legionella pneumophila Targets Activated Rab5 and Rab22 to Interfere with Endosomal Trafficking in Macrophages
Upon phagocytosis, Legionella pneumophila translocates numerous effector proteins into host cells to perturb cellular metabolism… 
Highly Cited
2006
Highly Cited
2006
The Rab5 Guanine Nucleotide Exchange Factor Rabex-5 Binds Ubiquitin (Ub) and Functions as a Ub Ligase through an Atypical Ub-interacting Motif and a Zinc Finger Domain*
Rabex-5, the mammalian orthologue of yeast Vps9p, is a guanine nucleotide exchange factor for Rab5. Rabex-5 forms a tight complex… 
Highly Cited
2001
Highly Cited
2001
Functional synergy between Rab5 effector Rabaptin-5 and exchange factor Rabex-5 when physically associated in a complex.
Rab GTPases are central elements of the vesicular transport machinery. An emerging view is that downstream effectors of these… 
Highly Cited
2001
Highly Cited
2001
Rabaptin-5 is a novel fusion partner to platelet-derived growth factor beta receptor in chronic myelomonocytic leukemia.
Chromosomal translocations involving the platelet-derived growth factor beta receptor (PDGFbetaR) gene have been reported in some… 
Highly Cited
2001
Highly Cited
2001
Identification of rabaptin‐5, rabex‐5, and GM130 as putative effectors of rab33b, a regulator of retrograde traffic between the Golgi apparatus and ER
Highly Cited
2000
Highly Cited
2000
Selective Membrane Recruitment of EEA1 Suggests a Role in Directional Transport of Clathrin-coated Vesicles to Early Endosomes*
The molecular mechanisms ensuring directionality of endocytic membrane trafficking between transport vesicles and target… 
Highly Cited
1998
Highly Cited
1998
The Neuronal Growth-Associated Protein GAP-43 Interacts with Rabaptin-5 and Participates in Endocytosis
Structural plasticity of nerve cells is a requirement for activity-dependent changes in the brain. The growth-associated protein… 
Highly Cited
1998
Highly Cited
1998
Two distinct effectors of the small GTPase Rab5 cooperate in endocytic membrane fusion
Using the yeast two‐hybrid system, we have identified a novel 62 kDa coiled‐coil protein that specifically interacts with the GTP… 
Highly Cited
1997
Highly Cited
1997
Cleavage of Rabaptin‐5 blocks endosome fusion during apoptosis
Cells undergoing apoptosis exhibit striking changes in membrane organization, including plasma membrane blebbing and invagination… 
Highly Cited
1995
Highly Cited
1995
Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion
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