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RABEP1 protein, human

Known as: neurocrescin protein, human, RAB5EP protein, human, neurocrescin, NOGF protein, human 
Rab GTPase-binding effector protein 1 (862 aa, ~99 kDa) is encoded by the human RABEP1 gene. This protein is involved in both the mediation of… 
National Institutes of Health

Related topics

Related topics

8 relations
CytoplasmEarly endosomeEndocytosisRABEP1 gene

Broader (1)

Vesicular Transport Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Rabaptin-5 regulates receptor expression and functional activation in mast cells.
Rab5 is a small GTPase that regulates early endocytic events and is activated by RabGEF1/Rabex-5. Rabaptin-5, a Rab5 interacting… 
2007
2007
Roles of RabGEF1/Rabex-5 domains in regulating Fc epsilon RI surface expression and Fc epsilon RI-dependent responses in mast cells.
RabGEF1/Rabex-5, a guanine nucleotide exchange factor (GEF) for the endocytic pathway regulator, Rab5, contains a Vps9 domain, an… 
2006
2006
Apoptotic Cleavage of Rabaptin-5-like Proteins and a Model for Rabaptin-5 Inactivation in Apoptosis
Intracellular membrane transport from the plasma membrane is one of the processes affected in apoptotic cells. Apoptotic… 
2005
2005
Expression of calpastatin, minopontin, NIPSNAP1, rabaptin-5 and neuronatin in the phenylketonuria (PKU) mouse brain: Possible role on cognitive defect seen in PKU
2005
2005
High resolution crystal structures of human Rab4a in its active and inactive conformations
2004
2004
The Rab5 effector Rabaptin‐5 and its isoform Rabaptin‐5δ differ in their ability to interact with the small GTPase Rab4
Rabaptin‐5 is an effector for the small GTPase Rab5, a regulator of the early steps in endocytosis. In addition, Rabaptin‐5… 
2003
2003
The interaction of the human GGA1 GAT domain with rabaptin-5 is mediated by residues on its three-helix bundle.
GGA proteins regulate clathrin-coated vesicle trafficking by interacting with multiple proteins during vesicle assembly. As part… 
2002
2002
Gamma-adaptin interacts directly with Rabaptin-5 through its ear domain.
In yeast two-hybrid screening using gamma1-adaptin, a subunit of the AP-1 adaptor complex of clathrin-coated vesicles derived… 
2002
2002
Multiple Rabaptin-5-like transcripts.
1999
1999
Human Rabaptin-5 Is Selectively Cleaved by Caspase-3 during Apoptosis*
We have previously shown that Xenopusrabaptin-5 is cleaved in apoptotic extracts, with a concomitant reduction in the ability of… 
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