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Quinacrine

Known as: N(4)-(6-chloro-2-Methoxy-9-acridinyl)-N(1),N(1)-diethyl-1,4-pentanediamine, 6-chloro-9-((4-(Diethylamino)-1-methylbutyl)amino)-2-methoxyacridine, 3-chloro-7-Methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine 
An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an… 
National Institutes of Health

Related topics

Related topics

26 relations

Narrower (5)

AcrichineAtabrineQuinacrine DihydrochlorideQuinacrine Dihydrochloride, Dihydrate

Broader (9)

AcridinesAminacrineAminoacridinesAnthelmintics
Ethosuximide / QuinacrineGiardiasisIn BloodMalaria, Falciparum

Papers overview

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Highly Cited
1986
Highly Cited
1986
Identification of distinct activation pathways of the human neutrophil NADPH-oxidase.
The stimulation of the human neutrophil NADPH-oxidase is initiated by a variety of agonists, which appear to utilize more than… 
Highly Cited
1982
Highly Cited
1982
The stimulation of protein degradation in muscle by Ca2+ is mediated by prostaglandin E2 and does not require the calcium-activated protease.
Highly Cited
1982
Highly Cited
1982
KININS STIMULATE NET CHLORIDE SECRETION BY THE RAT COLON
1 Short circuit current (SCC), transepithelial conductance and ion fluxes were measured across the isolated descending colon of… 
Highly Cited
1982
Highly Cited
1982
Studies of phospholipase A2 related to the hamster sperm acrosome reaction.
This report describes studies of innate and exogenous phospholipase A2 related to the acrosome reaction of golden hamster cauda… 
Highly Cited
1981
Highly Cited
1981
The initial action of thrombin on platelets. Conversion of phosphatidylinositol to phosphatidic acid preceding the production of arachidonic acid.
Highly Cited
1979
Highly Cited
1979
Further evidence in support of a role for hamster sperm hydrolytic enzymes in the acrosome reaction.
The effects of trypsin inhibitors and phospholipase inhibitors on the acrosome reaction of washed cauda epididymal sperm of… 
Highly Cited
1978
Highly Cited
1978
A study of H+ transport in gastric microsomal vesicles using fluorescent probes.
Highly Cited
1977
Highly Cited
1977
Prostaglandin E2 biosynthesis by rabbit renomedullary interstitial cells in tissue culture. Mechanism of stimulation by angiotensin II, bradykinin, and arginine vasopressin.
Highly Cited
1970
Highly Cited
1970
Photophosphorylation in digitonin subchloroplast particles. Absence of a light-induced pH shift.
Highly Cited
1966
Highly Cited
1966
Effect of salts and electron transport on the conformation of isolated chloroplasts. I. Light-scattering and volume changes.
Whole chloroplasts isolated from the leaves of spinach (Spinacia oleracea L.) exhibit 2 types of conformational change during… 
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