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Quinacrine Dihydrochloride

Known as: Atabrine Dihydrochloride, Mepacrine Dihydrochloride, SN 390 
 
National Institutes of Health

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2 relations

Broader (1)

Quinacrine
Quinacrine Monohydrochloride

Papers overview

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2009
2009
Direct effect of ropivacaine involves lipoxygenase pathway activation in rat aortic smooth muscle
PurposeRopivacaine is a long-acting amino-amide local anesthetic that induces vasoconstriction in vitro and in vivo. The aim of… Expand
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2009
2009
Direct effect of dexmedetomidine on rat isolated aorta involves endothelial nitric oxide synthesis and activation of the lipoxygenase pathway.
1. The aims of the present in vitro study were to examine the roles of pathways associated with arachidonic acid metabolism in… Expand
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2000
2000
Quinacrine dihydrochloride, the non-surgical female sterilant induces dicentrics, rings, and marker chromosomes in human peripheral blood lymphocytes treated in vitro: a preliminary report.
During the last decade, quinacrine dihydrochloride (QDH) has been promoted for clinical trials as a much needed non-surgical… Expand
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1991
1991
Antimalarial activity of optical isomers of quinacrine dihydrochloride against chloroquine-sensitive and -resistant Plasmodium falciparum in vitro.
Both enantiomers of quinacrine and the racemic form of the drug showed equal activity in vitro against chloroquine-sensitive and… Expand
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1986
1986
Differential effects of mepacrine, chloroquine and hydroxychloroquine on superoxide anion generation, phospholipid methylation and arachidonic acid release by human blood monocytes.
The 4-aminoquinolines chloroquine (CQ) and hydroxychloroquine (HCQ), and previously the 9-aminoacridine mepacrine (quinacrine… Expand
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1979
1979
Metmyoglobin reductase. Identification and purification of a reduced nicotinamide adenine dinucleotide-dependent enzyme from bovine heart which reduces metmyoglobin.
Beef heart muscle has been found to contain an enzyme which will rapidly and directly reduce metmyoglobin in vitro. Reduction… Expand
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Highly Cited
1979
Highly Cited
1979
The mutagenic activity of 61 agents as determined by the micronucleus, Salmonella, and sperm abnormality assays.
A comparison of two rapid and inexpensive in vivo mammalian assays and the Ames Salmonella assay is presented for 61 agents… Expand
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1971
1971
Identification of G group anomalies in Down's syndrome by quinacrine dihydrochloride fluorescence staining
Summary9 patients with regular trisomic Down's syndrome, 3 female carriers from different t (DqGq) families and 2 carriers from… Expand
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1966
1966
Uptake of Iodine-131-labelled Atabrine by Ehrlich Ascites Tumour and by Sarcoma S-180 BALB
ACKERMAN1,2 reported a selective incorporation of iodine-131-labelled atabrine by lung and subcutaneous Novikoff hepatoma and… Expand
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1947
1947
Effect of quinacrine (atabrine) on the central nervous system; clinical and electroencephalographic studies.
THE INTRODUCTION of quinacrine hydrochloride (atabrine dihydrochloride) as an antimalarial agent has brought with it the usual… Expand
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