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Protein Tyrosine Phosphatase

Known as: [Phosphotyrosine]Protein Phosphatase, Phosphatase, Tyrosyl Phosphoprotein, Protein Tyrosine Phosphatases [Chemical/Ingredient] 
Encoded by Protein Tyrosine Phosphatase Genes, Protein Tyrosine Phosphatases are a group of enzymes that specifically remove tyrosine-bound phosphate… 
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (27)

ACP1 protein, humanCDC14A protein, mouseClp1 protein, S. pombeCpsB protein, Streptococcus pneumoniae
DephosphorylationEnzyme GeneEsterase GeneHydrolase

Broader (1)

Phosphoric Monoester Hydrolases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
Molecular dynamics simulations of interaction between protein-tyrosine phosphatase 1B and a bidentate inhibitor
AbstractAim:To investigate the dynamic properties of protein-tyrosine phosphatase (PTP) 1B and reveal the structural factors… 
Highly Cited
2002
Highly Cited
2002
Receptor-Specific Regulation of Phosphatidylinositol 3′-Kinase Activation by the Protein Tyrosine Phosphatase Shp2
ABSTRACT Receptor tyrosine kinases (RTKs) play distinct roles in multiple biological systems. Many RTKs transmit similar signals… 
Highly Cited
1999
Highly Cited
1999
Cloning and characterization of a lymphoid-specific, inducible human protein tyrosine phosphatase, Lyp.
Protein tyrosine phosphatases act in conjunction with protein kinases to regulate the tyrosine phosphorylation events that… 
Review
1999
Review
1999
Regulation of immune responses through inhibitory receptors.
Major histocompatibility complex class I-specific inhibitory receptors on natural killer cells prevent the lysis of healthy… 
Highly Cited
1998
Highly Cited
1998
Specific and reversible inactivation of protein tyrosine phosphatases by hydrogen peroxide: evidence for a sulfenic acid intermediate and implications for redox regulation.
Protein tyrosine phosphatases (PTPs) catalyze the hydrolysis of phosphotyrosine from specific signal-transducing proteins… 
Highly Cited
1996
Highly Cited
1996
A novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesion
Protein tyrosine phosphatases (PTPases), such as SHP-1 and SHP-2, that contain Src homology 2 (SH2) domains play important roles… 
Highly Cited
1995
Highly Cited
1995
A role in B cell activation for CD22 and the protein tyrosine phosphatase SHP.
CD22 is a membrane immunoglobulin (mIg)-associated protein of B cells. CD22 is tyrosine-phosphorylated when mIg is ligated… 
Highly Cited
1993
Highly Cited
1993
Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation.
Regulation of cell proliferation, differentiation, and metabolic homeostasis is associated with the phosphorylation and… 
Highly Cited
1992
Highly Cited
1992
Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase
REACTIVE oxygen species have been implicated both in the ageing process and in degenerative diseases, including arthritis and… 
Highly Cited
1991
Highly Cited
1991
cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2
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