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Protein Tyrosine Phosphatase

Known as: [Phosphotyrosine]Protein Phosphatase, Phosphatase, Tyrosyl Phosphoprotein, Protein Tyrosine Phosphatases [Chemical/Ingredient] 
Encoded by Protein Tyrosine Phosphatase Genes, Protein Tyrosine Phosphatases are a group of enzymes that specifically remove tyrosine-bound phosphate… Expand
National Institutes of Health

Papers overview

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Review
2006
Review
2006
  • N. Tonks
  • Nature Reviews Molecular Cell Biology
  • 2006
  • Corpus ID: 1302726
The protein tyrosine phosphatase (PTP) superfamily of enzymes functions in a coordinated manner with protein tyrosine kinases to… Expand
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Review
2004
Review
2004
Tyrosine phosphorylation is catalyzed by protein tyrosine kinases, which are represented by 90 genes in the human genome. Here… Expand
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Highly Cited
2004
Highly Cited
2004
Rheumatoid arthritis (RA) is the most common systemic autoimmune disease, affecting approximately 1% of the adult population… Expand
Highly Cited
2004
Highly Cited
2004
We report that a single-nucleotide polymorphism (SNP) in the gene (PTPN22) encoding the lymphoid protein tyrosine phosphatase… Expand
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Highly Cited
2003
Highly Cited
2003
The second messenger hydrogen peroxide is required for optimal activation of numerous signal transduction pathways, particularly… Expand
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Highly Cited
2002
Highly Cited
2002
We have investigated the regulation of protein tyrosine phosphatases (PTPs) by reactive oxygen species (ROS) in a cellular… Expand
Highly Cited
2001
Highly Cited
2001
Noonan syndrome (MIM 163950) is an autosomal dominant disorder characterized by dysmorphic facial features, proportionate short… Expand
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Highly Cited
2001
Highly Cited
2001
Helicobacter pylori CagA protein is associated with severe gastritis and gastric carcinoma. CagA is injected from the attached… Expand
Highly Cited
2000
Highly Cited
2000
ABSTRACT Protein-tyrosine phosphatase 1B (PTP-1B) is a major protein-tyrosine phosphatase that has been implicated in the… Expand
Highly Cited
1998
Highly Cited
1998
Stimulation of various cells with growth factors results in a transient increase in the intracellular concentration of H2O2 that… Expand