Protein Tyrosine Phosphatase
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The protein tyrosine phosphatase (PTP) superfamily of enzymes functions in a coordinated manner with protein tyrosine kinases to… Expand Tyrosine phosphorylation is catalyzed by protein tyrosine kinases, which are represented by 90 genes in the human genome. Here… Expand Rheumatoid arthritis (RA) is the most common systemic autoimmune disease, affecting approximately 1% of the adult population… Expand We report that a single-nucleotide polymorphism (SNP) in the gene (PTPN22) encoding the lymphoid protein tyrosine phosphatase… Expand The second messenger hydrogen peroxide is required for optimal activation of numerous signal transduction pathways, particularly… Expand We have investigated the regulation of protein tyrosine phosphatases (PTPs) by reactive oxygen species (ROS) in a cellular… Expand Noonan syndrome (MIM 163950) is an autosomal dominant disorder characterized by dysmorphic facial features, proportionate short… Expand Helicobacter pylori CagA protein is associated with severe gastritis and gastric carcinoma. CagA is injected from the attached… Expand ABSTRACT Protein-tyrosine phosphatase 1B (PTP-1B) is a major protein-tyrosine phosphatase that has been implicated in the… Expand Stimulation of various cells with growth factors results in a transient increase in the intracellular concentration of H2O2 that… Expand