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Protein S

Known as: Protein S [Chemical/Ingredient], Protein S, Cofactor, Protein S, Vitamin K-Dependent 
The vitamin K-dependent cofactor of activated PROTEIN C. Together with protein C, it inhibits the action of factors VIIIa and Va. A deficiency in… 
National Institutes of Health

Related topics

Related topics

19 relations

Broader (4)

AnticoagulantsFibrinolytic AgentsGlycoproteinsPROS1 gene

Narrower (4)

Kcentraprotein S Heerlenprotein S Tokushimaprotein S, human
Process of secretionProtein S measurementVitamin KVitronectin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Protein S.
Protein S (PS) is a vitamin K-dependent plasma glycoprotein. Around 60-70% of PS in plasma is noncovalently bound to C4-binding… 
2010
2010
Dependence on Vitamin K-dependent Protein S for Eukaryotic Cell Secretion of the β-Chain of C4b-binding Protein*
The anticoagulant vitamin K-dependent protein S (PS) circulates in plasma in two forms, 30% free and 70% being bound to the… 
2006
2006
The Constitutive Expression of Anticoagulant Protein S Is Regulated through Multiple Binding Sites for Sp1 and Sp3 Transcription Factors in the Protein S Gene Promoter*
Protein S (PS) is a vitamin K-dependent plasma protein that inhibits blood coagulation by serving as a nonenzymatic cofactor for… 
2006
2006
Lipopolysaccharide‐induced decreased protein S expression in liver cells is mediated by MEK/ERK signaling and NFκB activation: involvement of membrane‐bound CD14 and toll‐like receptor‐4
Summary.  Background: The vitamin K‐dependent protein S (PS), mainly synthesized in hepatocytes and endothelial cells, plays a… 
2001
2001
DNA sequence analysis of protein S deficiency--identification of four point mutations in twelve Japanese subjects.
The molecular basis for the hereditary type I protein S (PS) deficiency was investigated. DNA sequence analysis of 12 patients… 
2001
2001
Implication of protein S thrombin-sensitive region with membrane binding via conformational changes in the gamma-carboxyglutamic acid-rich domain.
In the vitamin K-dependent protein family, only protein S (PS) contains a thrombin-sensitive region (TSR), located between the… 
1997
1997
A theoretical model for the Gla-TSR-EGF-1 region of the anticoagulant cofactor protein S: From biostructural pathology to specie
Protein S (PS), which functions as a species-specific anticoagulant cofactor to activated protein C (APC), is a mosaic protein… 
1994
1994
First frameshift mutation in the active protein S gene associated with a quantitative hereditary deficiency.
The authors used a strategy combining the amplification-refractory mutations system (ARMS) and denaturing gradient gel… 
1988
1988
The Anticoagulant Properties of a Modified Form of Protein S
Summary Protein S (PS) is a vitamin K-dependent anticoagulant that acts as a cofactor to activated protein C (APC). To date PS… 
1986
1986
Prevalence of protein C (PC) and protein S (PS) deficiency in patients with thrombotic disease
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