Protein Kinase C

Known as: Phospholipid-Sensitive Calcium-Dependent Protein Kinase, Calcium Phospholipid-Dependent Protein Kinase, PKC 
An serine-threonine protein kinase that requires the presence of physiological concentrations of CALCIUM and membrane PHOSPHOLIPIDS. The additional… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Recent studies have shown that overweight and obesity play an important role in the development of osteoarthritis (OA). However… (More)
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Review
2007
Review
2007
Almost three decades after the discovery of protein kinase C (PKC), we still have only a partial understanding of how this family… (More)
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Highly Cited
2000
Highly Cited
2000
PAR (partitioning-defective) proteins, which were first identified in the nematode Caenorhabditis elegans, are essential for… (More)
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Highly Cited
2000
Highly Cited
2000
Recent studies have revealed that vascular cells can produce reactive oxygen species (ROS) through NAD(P)H oxidase, which may be… (More)
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Highly Cited
1999
Highly Cited
1999
To examine the mechanism by which free fatty acids (FFAs) induce insulin resistance in vivo, awake chronically catheterized rats… (More)
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Review
1998
Review
1998
Members of the mammalian protein kinase C (PKC) superfamily play key regulatory roles in a multitude of cellular processes… (More)
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Review
1998
Review
1998
Recent studies have identified that the activation of protein kinase C (PKC) and increased diacylglycerol (DAG) levels initiated… (More)
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Highly Cited
1995
Highly Cited
1995
The protein tyrosine kinase PYK2, which is highly expressed in the central nervous system, is rapidly phosphorylated on tyrosine… (More)
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Highly Cited
1993
Highly Cited
1993
Indolocarbazoles have been identified as novel inhibitors of protein kinase C (PKC), with Gö 6976 as one of its most potent and… (More)
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Highly Cited
1991
Highly Cited
1991
Staurosporine is the most potent inhibitor of protein kinase C (PKC) described in the literature with a half-maximal inhibitory… (More)
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